Autophagy, originally found in liver experiments, is a cellular process that degrades
damaged organelle or protein aggregation. This process frees cells from various stress …

Autophagy is an intracellular catabolic self-cannibalism that eliminates dysfunctional
cytoplasmic cargos by the fusion of cargo-containing autophagosomes with lysosomes to …

Background Resveratrol, a natural polyphenolic phytoalexin, has potent anti-tumor activity.
Recently, it was found to induce autophagy in cancer cells. However, the effects of …

Cyclopeptides or cyclic peptides are polypeptides formed by ring closing of terminal amino
acids. A large number of natural cyclopeptides have been reported to be highly effective …

Background Natural cyclopeptide RA-XII, isolated from Rubia yunnanensis, is a promising
chemotherapeutic agent for colon cancer. The photosensitizer protoporphyrin-IX attached …

Background: Liver cancer is one of the leading cancers in China. Rhein induces apoptosis
in various human cancer cells, but the underlying mechanism is still unknown. Methods: In …

Autophagy is an evolutionarily conserved lysosomal-dependent pathway for degrading
cytoplasmic proteins, macromolecules, and organelles. Autophagy-related genes (Atgs) are …

Macroautophagy/autophagy is the process of self-digestion through the lysosomes; it
disassembles unnecessary or dysfunctional long-lived proteins and damaged organelles for …

Inhibition of autophagy increases the sensitivity of tumor cells to radiotherapy and
chemotherapy and improves the therapeutic effect on tumors. Recently, photodynamic …

Background Periplocin is a monomeric compound that exhibits anti‐tumor activities. It is
extracted from Cortex Periplocae. Objective This study aimed at determining the effect of …