Intrinsically disordered protein regions and phase separation: sequence determinants of assembly or lack thereof.
EW Martin, AS Holehouse - Emerging topics in life sciences, 2020 - europepmc.org
Intrinsically disordered protein regions (IDRs)-regions that do not fold into a fixed three-
dimensional structure but instead exist in a heterogeneous ensemble of conformations-have …
dimensional structure but instead exist in a heterogeneous ensemble of conformations-have …
Adaptable hydrogel networks with reversible linkages for tissue engineering
H Wang, SC Heilshorn - Advanced Materials, 2015 - Wiley Online Library
Adaptable hydrogels have recently emerged as a promising platform for three‐dimensional
(3D) cell encapsulation and culture. In conventional, covalently crosslinked hydrogels …
(3D) cell encapsulation and culture. In conventional, covalently crosslinked hydrogels …
Structural determinants of Smad function in TGF-β signaling
Smad transcription factors are central to the signal transduction pathway that mediates the
numerous effects of the transforming growth factor β (TGF-β) superfamily of cytokines in …
numerous effects of the transforming growth factor β (TGF-β) superfamily of cytokines in …
Virus budding and the ESCRT pathway
J Votteler, WI Sundquist - Cell host & microbe, 2013 - cell.com
Enveloped viruses escape infected cells by budding through limiting membranes. In the
decade since the discovery that HIV recruits cellular ESCRT (endosomal sorting complexes …
decade since the discovery that HIV recruits cellular ESCRT (endosomal sorting complexes …
Multicomponent self-assembly as a tool to harness new properties from peptides and proteins in material design
BO Okesola, A Mata - Chemical Society Reviews, 2018 - pubs.rsc.org
Nature is enriched with a wide variety of complex, synergistic, and highly functional protein-
based multicomponent assemblies. As such, nature has served as a source of inspiration for …
based multicomponent assemblies. As such, nature has served as a source of inspiration for …
Retinoic acid receptors: from molecular mechanisms to cancer therapy
Retinoic acid (RA), the major bioactive metabolite of retinol or vitamin A, induces a spectrum
of pleiotropic effects in cell growth and differentiation that are relevant for embryonic …
of pleiotropic effects in cell growth and differentiation that are relevant for embryonic …
Polyproline-II helix in proteins: structure and function
AA Adzhubei, MJE Sternberg, AA Makarov - Journal of molecular biology, 2013 - Elsevier
The poly-l-proline type II (PPII) helix in recent years has emerged clearly as a structural class
not only of fibrillar proteins (in collagen, PPII is a dominant conformation) but also of the …
not only of fibrillar proteins (in collagen, PPII is a dominant conformation) but also of the …
[HTML][HTML] Invited review: Caseins and the casein micelle: Their biological functions, structures, and behavior in foods
A typical casein micelle contains thousands of casein molecules, most of which form
thermodynamically stable complexes with nanoclusters of amorphous calcium phosphate …
thermodynamically stable complexes with nanoclusters of amorphous calcium phosphate …
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
Coordination between cell proliferation and cell death is essential to maintain homeostasis
in multicellular organisms. In Drosophila, these two processes are regulated by a pathway …
in multicellular organisms. In Drosophila, these two processes are regulated by a pathway …
Epithelial sodium channel (ENaC) family: Phylogeny, structure–function, tissue distribution, and associated inherited diseases
I Hanukoglu, A Hanukoglu - Gene, 2016 - Elsevier
The epithelial sodium channel (ENaC) is composed of three homologous subunits and
allows the flow of Na+ ions across high resistance epithelia, maintaining body salt and water …
allows the flow of Na+ ions across high resistance epithelia, maintaining body salt and water …