Hyaluronic acid: a key ingredient in the therapy of inflammation

A Marinho, C Nunes, S Reis - Biomolecules, 2021 - mdpi.com
Hyaluronic acid (HA) is a natural polymer, produced endogenously by the human body,
which has unique physicochemical and biological properties, exhibiting desirable …

[HTML][HTML] Strategic approaches for colon targeted drug delivery: an overview of recent advancements

SH Lee, R Bajracharya, JY Min, JW Han, BJ Park… - Pharmaceutics, 2020 - mdpi.com
Colon targeted drug delivery systems have gained a great deal of attention as potential
carriers for the local treatment of colonic diseases with reduced systemic side effects and …

Oral delivery of natural active small molecules by polymeric nanoparticles for the treatment of inflammatory bowel diseases

M Zu, Y Ma, B Cannup, D **e, Y Jung, J Zhang… - Advanced Drug Delivery …, 2021 - Elsevier
The incidence of inflammatory bowel disease (IBD) is rapidly rising throughout the world.
Although tremendous efforts have been made, limited therapeutics are available for IBD …

[HTML][HTML] Biological drug and drug delivery-mediated immunotherapy

Q **ao, X Li, Y Li, Z Wu, C Xu, Z Chen, W He - Acta Pharmaceutica Sinica B, 2021 - Elsevier
The initiation and development of major inflammatory diseases, ie, cancer, vascular
inflammation, and some autoimmune diseases are closely linked to the immune system …

ROS-responsive hyaluronic acid hydrogel for targeted delivery of probiotics to relieve colitis

L Huang, J Wang, L Kong, X Wang, Q Li… - International Journal of …, 2022 - Elsevier
Probiotics are generally used as therapeutic intervention in inflammatory bowel disease.
However, the low survival rate in harsh gastrointestinal environment and limited retention in …

Advanced nanomedicines for the treatment of inflammatory diseases

R Brusini, M Varna, P Couvreur - Advanced drug delivery reviews, 2020 - Elsevier
Inflammation, a common feature of many diseases, is an essential immune response that
enables survival and maintains tissue homeostasis. However, in some conditions, the …

Absorption, metabolism, and functions of hyaluronic acid and its therapeutic prospects in combination with microorganisms: A review

X Zheng, B Wang, X Tang, B Mao, Q Zhang… - Carbohydrate …, 2023 - Elsevier
Hyaluronic acid (HA) is key to the stability of the internal environment of tissues. HA content
in tissues gradually decreases with age, causing age-related health problems. Exogenous …

Nanoparticles for oral delivery: targeted therapy for inflammatory bowel disease

D Li, M Yang, H Xu, M Zhu, Y Zhang, C Tian… - Journal of Materials …, 2022 - pubs.rsc.org
As a group of chronic and idiopathic gastrointestinal (GI) disorders, inflammatory bowel
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …

Oral delivery of nanoparticles loaded with ginger active compound, 6-shogaol, attenuates ulcerative colitis and promotes wound healing in a murine model of …

M Zhang, C Xu, D Liu, MK Han, L Wang… - Journal of Crohn's and …, 2018 - academic.oup.com
Abstract Background and Aims Oral drug delivery is the most attractive pathway for
ulcerative colitis [UC] therapy, since it has many advantages. However, this strategy has …

Natural polysaccharides based self-assembled nanoparticles for biomedical applications–A review

Y Fan, Y Liu, Y Wu, F Dai, M Yuan, F Wang… - International Journal of …, 2021 - Elsevier
In recent years, nanoparticles (NPs) derived from the self-assembly of natural
polysaccharides have shown great potential in the biomedical field. Here, we described …