Cryoglobulinaemia
Cryoglobulinaemia refers to the serum presence of cryoglobulins, which are defined as
immunoglobulins that precipitate at temperatures< 37° C. Type I cryoglobulinaemia consists …
immunoglobulins that precipitate at temperatures< 37° C. Type I cryoglobulinaemia consists …
[HTML][HTML] Hepatitis C virus: Morphogenesis, infection and therapy
Hepatitis C virus (HCV) is a major cause of liver diseases including liver cirrhosis and
hepatocellular carcinoma. Approximately 3% of the world population is infected with HCV …
hepatocellular carcinoma. Approximately 3% of the world population is infected with HCV …
[PDF][PDF] Structural biology of hepatitis C virus
F Penin, J Dubuisson, FA Rey, D Moradpour… - …, 2004 - Wiley Online Library
Hepatitis C virus (HCV) causes acute and chronic liver disease in humans, including chronic
hepatitis, cirrhosis, and hepatocellular carcinoma. Studies of this virus have been hampered …
hepatitis, cirrhosis, and hepatocellular carcinoma. Studies of this virus have been hampered …
Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor
Several cell surface molecules have been proposed as receptor candidates, mediating cell
entry of hepatitis C virus (HCV) on the basis of their physical association with virions or with …
entry of hepatitis C virus (HCV) on the basis of their physical association with virions or with …
CD81 is required for hepatitis C virus glycoprotein-mediated viral infection
ABSTRACT CD81 has been described as a putative receptor for hepatitis C virus (HCV);
however, its role in HCV cell entry has not been characterized due to the lack of an efficient …
however, its role in HCV cell entry has not been characterized due to the lack of an efficient …
Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR
S Pöhlmann, J Zhang, F Baribaud, Z Chen… - Journal of …, 2003 - Am Soc Microbiol
ABSTRACT DC-SIGN and DC-SIGNR are two closely related membrane-associated C-type
lectins that bind human immunodeficiency virus (HIV) envelope glycoprotein with high …
lectins that bind human immunodeficiency virus (HIV) envelope glycoprotein with high …
The hepatitis C virus life cycle as a target for new antiviral therapies
JM Pawlotsky, S Chevaliez, JG McHutchison - Gastroenterology, 2007 - Elsevier
The burden of disease consequent to hepatitis C virus (HCV) infection has been well
described and is expected to increase dramatically over the next decade. Current approved …
described and is expected to increase dramatically over the next decade. Current approved …
Hepatitis C virus hypervariable region 1 modulates receptor interactions, conceals the CD81 binding site, and protects conserved neutralizing epitopes
D Bankwitz, E Steinmann, J Bitzegeio, S Ciesek… - Journal of …, 2010 - Am Soc Microbiol
The variability of the hepatitis C virus (HCV), which likely contributes to immune escape, is
most pronounced in hypervariable region 1 (HVR1) of viral envelope protein 2. This domain …
most pronounced in hypervariable region 1 (HVR1) of viral envelope protein 2. This domain …
Identification of conserved residues in the E2 envelope glycoprotein of the hepatitis C virus that are critical for CD81 binding
Hepatitis C virus (HCV) cell entry involves interaction between the viral envelope
glycoprotein E2 and the cell surface receptor CD81. Knowledge of conserved E2 …
glycoprotein E2 and the cell surface receptor CD81. Knowledge of conserved E2 …
[HTML][HTML] Hepatitis C virus proteins
J Dubuisson - World journal of gastroenterology: WJG, 2007 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) encodes a single polyprotein, which is processed by cellular and
viral proteases to generate 10 polypeptides. The HCV genome also contains an …
viral proteases to generate 10 polypeptides. The HCV genome also contains an …