Although no randomized studies have demonstrated a positive impact of therapeutic drug
monitoring (TDM) on clinical outcome in epilepsy, evidence from nonrandomized studies …

Epilepsy is a recurrent long-term illness occurring in approximately 1.0% of the world's
population. There are currently about 29 approved antiepileptic drugs for the management …

The aim of the study was to produce a Polyvinyl chloride-based membrane containing a
polymer imprinted with a valproic acid molecule which was directly coated on a graphite …

Bipolar disorder (BD) is a long-term illness with mood swings which are characterized by
recurrent episodes of mania/hypomania and depression, with variable interpolations of …

The purpose of the present study was to evaluate the acute anticonvulsant effects of caprylic
acid (CA), the main constituent of the medium-chain triglyceride ketogenic diet (MCT KD), in …

This study presents an efficient high-performance liquid chromatography with ultraviolet
detection (HPLC-UV) method for monitoring valproic acid (VPA) level in human plasma. This …

Plasma concentration–time data obtained after an oral single dose of 500-mg valproic acid
(VPA) in a delayed release formulation was used to model enterohepatic cycling of the drug …

Valproic acid (VPA) dosing needs to be individualized for epilepsy patients through
therapeutic drug monitoring (TDM). The patients must show up in the clinic at the therapeutic …

Valproic acid, a branched short‐chain fatty acid, has numerous action mechanisms which
turn it into a broad spectrum anticonvulsant drug and make its use possible in some other …

In this study, to explore a potential sensor for the valproic acid drug, pure and doped zinc
oxide nanoclusters (Zn 12 O 12, AlZn 11 O 12, and, GaZn 11 O 12) were utilized in the gas …