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Bile acids and their derivatives as potential modifiers of drug release and pharmacokinetic profiles
Bile acids have received considerable interest in the drug delivery research due to their
peculiar physicochemical properties and biocompatibility. The main advantage of bile acids …
peculiar physicochemical properties and biocompatibility. The main advantage of bile acids …
Self-assembly in aqueous bile salt solutions
D Madenci, SU Egelhaaf - Current Opinion in Colloid & Interface Science, 2010 - Elsevier
The salts of bile acids (“bile salts”) self-assemble in aqueous solution, similar to classical
amphiphiles. The micellization is not only driven by the hydrophobic effect, but also …
amphiphiles. The micellization is not only driven by the hydrophobic effect, but also …
Bile acids and bile acid derivatives: use in drug delivery systems and as therapeutic agents
C Faustino, C Serafim, P Rijo… - Expert Opinion on Drug …, 2016 - Taylor & Francis
Introduction: Bile acids are biological surfactants and signaling molecules with important
paracrine and endocrine functions. The enterohepatic organotropism of bile acids turns …
paracrine and endocrine functions. The enterohepatic organotropism of bile acids turns …
Binary mixed micelles of hexadecyltrimethylammonium bromide–sodium deoxycholate and dodecyltrimethylammonium bromide–sodium deoxycholate …
D Kumar, Z Farkaš Agatić, K Popović… - Industrial & …, 2024 - ACS Publications
In this paper, the thermodynamic properties of binary mixtures of the surfactants
hexadecyltrimethylammonium bromide (HA)–sodium deoxycholate (DC) and …
hexadecyltrimethylammonium bromide (HA)–sodium deoxycholate (DC) and …
Regular solution theory regarding sodium cholate and hexadecyltrimethylammonium bromide or dodecyltrimethylammonium bromide binary mixed micelles
The formation of binary mixed micelles of sodium cholate (SC)–
hexadecyltrimethylammonium bromide (HDTAB) and sodium cholate (SC) …
hexadecyltrimethylammonium bromide (HDTAB) and sodium cholate (SC) …
Solubilization and interaction studies of bile salts with surfactants and drugs: a review
NA Malik - Applied biochemistry and biotechnology, 2016 - Springer
In this review, bile salt, bile salt–surfactant, and bile salt–drug interactions and their
solubilization studies are mainly focused. Usefulness of bile salts in digestion, absorption …
solubilization studies are mainly focused. Usefulness of bile salts in digestion, absorption …
Interactions of phenothiazine drugs with bile salts: Micellization and binding studies
S Mahajan, RK Mahajan - Journal of colloid and interface science, 2012 - Elsevier
An evaluation of the interactions of phenothiazine tranquilizer drugs (promazine
hydrochloride; PMZ and promethazine hydrochloride; PMT) with bile salts viz., sodium …
hydrochloride; PMZ and promethazine hydrochloride; PMT) with bile salts viz., sodium …
The generalized identification of truly interfacial molecules (ITIM) algorithm for nonplanar interfaces
We present a generalized version of the ITIM algorithm for the identification of interfacial
molecules, which is able to treat arbitrarily shaped interfaces. The algorithm exploits the …
molecules, which is able to treat arbitrarily shaped interfaces. The algorithm exploits the …
Morphology of bile salts micelles and mixed micelles with lipolysis products, from scattering techniques and atomistic simulations
Hypotheses Bile salts (BS) are biosurfactants released into the small intestine, which play
key and contrasting roles in lipid digestion: they adsorb at interfaces and promote the …
key and contrasting roles in lipid digestion: they adsorb at interfaces and promote the …
Nanoemulsions of betulinic acid stabilized with modified phosphatidylcholine increase the stability of the nanosystems and the drug's bioavailability
DA Bravo-Alfaro, LR Ochoa-Rodríguez… - Colloids and Surfaces B …, 2025 - Elsevier
Betulinic acid (BA) is a natural compound with significant potential for treating various
diseases, including cancer and AIDS, and possesses additional anti-inflammatory and …
diseases, including cancer and AIDS, and possesses additional anti-inflammatory and …