Bile acids and their derivatives as potential modifiers of drug release and pharmacokinetic profiles

N Pavlović, S Goločorbin-Kon, M Ðanić… - Frontiers in …, 2018 - frontiersin.org
Bile acids have received considerable interest in the drug delivery research due to their
peculiar physicochemical properties and biocompatibility. The main advantage of bile acids …

Self-assembly in aqueous bile salt solutions

D Madenci, SU Egelhaaf - Current Opinion in Colloid & Interface Science, 2010 - Elsevier
The salts of bile acids (“bile salts”) self-assemble in aqueous solution, similar to classical
amphiphiles. The micellization is not only driven by the hydrophobic effect, but also …

Bile acids and bile acid derivatives: use in drug delivery systems and as therapeutic agents

C Faustino, C Serafim, P Rijo… - Expert Opinion on Drug …, 2016 - Taylor & Francis
Introduction: Bile acids are biological surfactants and signaling molecules with important
paracrine and endocrine functions. The enterohepatic organotropism of bile acids turns …

Binary mixed micelles of hexadecyltrimethylammonium bromide–sodium deoxycholate and dodecyltrimethylammonium bromide–sodium deoxycholate …

D Kumar, Z Farkaš Agatić, K Popović… - Industrial & …, 2024 - ACS Publications
In this paper, the thermodynamic properties of binary mixtures of the surfactants
hexadecyltrimethylammonium bromide (HA)–sodium deoxycholate (DC) and …

Regular solution theory regarding sodium cholate and hexadecyltrimethylammonium bromide or dodecyltrimethylammonium bromide binary mixed micelles

ZF Agatić, K Popović, D Kumar, D Škorić… - Journal of Molecular …, 2023 - Elsevier
The formation of binary mixed micelles of sodium cholate (SC)–
hexadecyltrimethylammonium bromide (HDTAB) and sodium cholate (SC) …

Solubilization and interaction studies of bile salts with surfactants and drugs: a review

NA Malik - Applied biochemistry and biotechnology, 2016 - Springer
In this review, bile salt, bile salt–surfactant, and bile salt–drug interactions and their
solubilization studies are mainly focused. Usefulness of bile salts in digestion, absorption …

Interactions of phenothiazine drugs with bile salts: Micellization and binding studies

S Mahajan, RK Mahajan - Journal of colloid and interface science, 2012 - Elsevier
An evaluation of the interactions of phenothiazine tranquilizer drugs (promazine
hydrochloride; PMZ and promethazine hydrochloride; PMT) with bile salts viz., sodium …

The generalized identification of truly interfacial molecules (ITIM) algorithm for nonplanar interfaces

M Sega, SS Kantorovich, P Jedlovszky… - The Journal of chemical …, 2013 - pubs.aip.org
We present a generalized version of the ITIM algorithm for the identification of interfacial
molecules, which is able to treat arbitrarily shaped interfaces. The algorithm exploits the …

Morphology of bile salts micelles and mixed micelles with lipolysis products, from scattering techniques and atomistic simulations

O Pabois, RM Ziolek, CD Lorenz, S Prévost… - Journal of Colloid and …, 2021 - Elsevier
Hypotheses Bile salts (BS) are biosurfactants released into the small intestine, which play
key and contrasting roles in lipid digestion: they adsorb at interfaces and promote the …

Nanoemulsions of betulinic acid stabilized with modified phosphatidylcholine increase the stability of the nanosystems and the drug's bioavailability

DA Bravo-Alfaro, LR Ochoa-Rodríguez… - Colloids and Surfaces B …, 2025 - Elsevier
Betulinic acid (BA) is a natural compound with significant potential for treating various
diseases, including cancer and AIDS, and possesses additional anti-inflammatory and …