Diabetes, a complex multisystem metabolic disorder characterized by hyperglycemia, leads
to complications that reduce quality of life and increase mortality. Diabetes pathophysiology …

Background Heterogeneity in type 2 diabetes presentation and progression suggests that
precision medicine interventions could improve clinical outcomes. We undertook a …

Primary diabetes care and diabetic retinopathy (DR) screening persist as major public
health challenges due to a shortage of trained primary care physicians (PCPs), particularly …

Immunotherapy targeting the autoimmune process in type 1 diabetes (T1D) can delay the
loss of β-cells but needs to have minimal adverse effects to be an adjunct to insulin in the …

Gestational diabetes is the most common medical complication in pregnancy. Historically,
gestational diabetes was considered a pregnancy complication involving treatment of rising …

Artificial intelligence (AI) use in diabetes care is increasingly being explored to personalise
care for people with diabetes and adapt treatments for complex presentations. However, the …

Precision medicine should aspire to reduce error and improve accuracy in medical and
health recommendations by comparison with contemporary practice, while maintaining …

Abstract Type 2 diabetes (T2D) is a multifactorial disease with substantial genetic risk, for
which the underlying biological mechanisms are not fully understood. In this study, we …

A global initiative to deliver precision health in diabetes | Nature Medicine Skip to main content
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Abstract Background Type 1 diabetes (T1D) results from immune-mediated destruction of
insulin-producing beta cells. Prevention efforts have focused on immune modulation and …