[HTML][HTML] Integrative multi-omics and systems bioinformatics in translational neuroscience: A data mining perspective
Bioinformatic analysis of large and complex omics datasets has become increasingly useful
in modern day biology by providing a great depth of information, with its application to …
in modern day biology by providing a great depth of information, with its application to …
Intracellular spatial transcriptomic analysis toolkit (InSTAnT)
Imaging-based spatial transcriptomics technologies such as Multiplexed error-robust
fluorescence in situ hybridization (MERFISH) can capture cellular processes in unparalleled …
fluorescence in situ hybridization (MERFISH) can capture cellular processes in unparalleled …
Advances in targeting cancer-associated fibroblasts through single-cell spatial transcriptomic sequencing
P Lyu, X Gu, F Wang, H Sun, Q Zhou, S Yang… - Biomarker …, 2024 - Springer
Cancer-associated fibroblasts (CAFs) are the major components of the tumor
microenvironment and are related to tumor proliferation, metastasis, relapse, and drug …
microenvironment and are related to tumor proliferation, metastasis, relapse, and drug …
Padlock Probe–Based Targeted In Situ Sequencing: Overview of Methods and Applications
Elucidating spatiotemporal changes in gene expression has been an essential goal in
studies of health, development, and disease. In the emerging field of spatially resolved …
studies of health, development, and disease. In the emerging field of spatially resolved …
FISHFactor: a probabilistic factor model for spatial transcriptomics data with subcellular resolution
Motivation Factor analysis is a widely used tool for unsupervised dimensionality reduction of
high-throughput datasets in molecular biology, with recently proposed extensions designed …
high-throughput datasets in molecular biology, with recently proposed extensions designed …
Spaco: A comprehensive tool for coloring spatial data at single-cell resolution
Z **g, Q Zhu, L Li, Y **e, X Wu, Q Fang, B Yang, B Dai… - Patterns, 2024 - cell.com
Understanding tissue architecture and niche-specific microenvironments in spatially
resolved transcriptomics (SRT) requires in situ annotation and labeling of cells. Effective …
resolved transcriptomics (SRT) requires in situ annotation and labeling of cells. Effective …
Statistical analysis supports pervasive RNA subcellular localization and alternative 3'UTR regulation
Targeted low-throughput studies have previously identified subcellular RNA localization as
necessary for cellular functions including polarization, and translocation. Furthermore, these …
necessary for cellular functions including polarization, and translocation. Furthermore, these …