The bottom‐up construction of a synthetic cell from nonliving building blocks capable of
mimicking cellular properties and behaviors helps to understand the particular biophysical …

The construction of artificial cells from inanimate molecular building blocks is one of the
grand challenges of our time. In addition to being used as simplified cell models to decipher …

The cytoskeleton is an essential component of a cell. It controls the cell shape, establishes
the internal organization, and performs vital biological functions. Building synthetic …

Conspectus Cells have evolved to be self-sustaining compartmentalized systems that
consist of many thousands of biomolecules and metabolites interacting in complex cycles …

Cytoskeletal elements, like actin and myosin, have been reconstituted inside lipid vesicles
toward the vision to reconstruct cells from the bottom up. Here, we realize the de novo …

Extracellular vesicles (EVs) are fundamental for intercellular communication and influence
nearly every process in cell physiology. However, because of their intricate molecular …

Fabrication of artificial biomimetic materials has attracted abundant attention. As one of the
subcategories of biomimetic materials, artificial cells are highly significant for multiple …

Building an artificial cell is a research area that is rigorously studied in the field of synthetic
biology. It has brought about much attention with the aim of ultimately constructing a natural …

A major goal of synthetic biology is to understand the transition between non-living matter
and life. The bottom-up development of an artificial cell would provide a minimal system with …

Abstract Development of regulated cellular processes and signaling methods in synthetic
cells is essential for their integration with living materials. Light is an attractive tool to achieve …