Protein design: From the aspect of water solubility and stability

R Qing, S Hao, E Smorodina, D **, A Zalevsky… - Chemical …, 2022 - ACS Publications
Water solubility and structural stability are key merits for proteins defined by the primary
sequence and 3D-conformation. Their manipulation represents important aspects of the …

Half a century of amyloids: past, present and future

PC Ke, R Zhou, LC Serpell, R Riek… - Chemical Society …, 2020 - pubs.rsc.org
Amyloid diseases are global epidemics with profound health, social and economic
implications and yet remain without a cure. This dire situation calls for research into the …

Supramolecular cancer nanotheranostics

J Zhou, L Rao, G Yu, TR Cook, X Chen… - Chemical Society …, 2021 - pubs.rsc.org
Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …

Do ionic liquids exhibit the required characteristics to dissolve, extract, stabilize, and purify proteins? Past-present-future assessment

P Bharmoria, AA Tietze, D Mondal, TS Kang… - Chemical …, 2024 - ACS Publications
Proteins are highly labile molecules, thus requiring the presence of appropriate solvents and
excipients in their liquid milieu to keep their stability and biological activity. In this field, ionic …

Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy

D Chowell, LGT Morris, CM Grigg, JK Weber… - Science, 2018 - science.org
CD8+ T cell–dependent killing of cancer cells requires efficient presentation of tumor
antigens by human leukocyte antigen class I (HLA-I) molecules. However, the extent to …

Antimicrobial mechanisms and effectiveness of graphene and graphene-functionalized biomaterials. A scope review

H Mohammed, A Kumar, E Bekyarova… - … in Bioengineering and …, 2020 - frontiersin.org
Bacterial infections represent nowadays the major reason of biomaterials implant failure,
however, most of the available implantable materials do not hold antimicrobial properties …

How water's properties are encoded in its molecular structure and energies

E Brini, CJ Fennell, M Fernandez-Serra… - Chemical …, 2017 - ACS Publications
How are water's material properties encoded within the structure of the water molecule? This
is pertinent to understanding Earth's living systems, its materials, its geochemistry and …

Mechanisms of the antimicrobial activities of graphene materials

X Zou, L Zhang, Z Wang, Y Luo - Journal of the american chemical …, 2016 - ACS Publications
A thorough understanding of the antimicrobial mechanisms of graphene materials (GMs) is
critical to the manipulation of highly efficient antimicrobial nanomaterials for future …

Overcoming the crystallization and designability issues in the ultrastable zirconium phosphonate framework system

T Zheng, Z Yang, D Gui, Z Liu, X Wang, X Dai… - Nature …, 2017 - nature.com
Metal-organic frameworks (MOFs) based on zirconium phosphonates exhibit superior
chemical stability suitable for applications under harsh conditions. These compounds mostly …

A mesoporous cationic thorium-organic framework that rapidly traps anionic persistent organic pollutants

Y Li, Z Yang, Y Wang, Z Bai, T Zheng, X Dai… - Nature …, 2017 - nature.com
Many environmental pollutants inherently exist in their anionic forms and are therefore
highly mobile in natural water systems. Cationic framework materials that can capture those …