Human cytochrome P450 (CYP) enzymes, as membrane-bound hemoproteins, play
important roles in the detoxification of drugs, cellular metabolism, and homeostasis. In …

Background: The cytochrome P450 (CYP) enzymes are membrane-bound hemoproteins
that play a pivotal role in the detoxification of xenobiotics, cellular metabolism and …

Many trace metals are essential micronutrients, but also potent toxins. Due to natural and
anthropogenic causes, vastly different trace metal concentrations occur in various habitats …

1. Learn how the body disposes of alcohol and its metabolites. 2. Discern some of the factors
that influence this process. 3. Learn how alcohol influences the metabolism of nutrients and …

Aedes aegypti and A. albopictus mosquitoes are vectors of important human disease
viruses, including dengue, yellow fever, chikungunya and Zika. Pyrethroid insecticides are …

There are 18 mammalian cytochrome P450 (CYP) families, which encode 57 genes in the
human genome. CYP2, CYP3 and CYP4 families contain far more genes than the other 15 …

Low levels of human medicines (pharmaceuticals) have been detected in many countries in
sewage treatment plant (STP) effluents, surface waters, seawaters, groundwater and some …

Abstract P-glycoprotein (P-gp) is an ATP-dependent efflux pump encoded by the MDR1
gene in humans, known to mediate multidrug resistance of neoplastic cells to cancer …

▪ Abstract The synthesis and excretion of bile acids comprise the major pathway of
cholesterol catabolism in mammals. Synthesis provides a direct means of converting …

Polycyclic aromatic hydrocarbons (PAHs) are formed during incomplete combustion.
Domestic wood burning and road traffic are the major sources of PAHs in Sweden. In …