Neurodegenerative diseases are the most common cause of dementia. Although their
underlying molecular pathologies have been identified, there is substantial heterogeneity in …

Neurological and psychiatric diseases have high degrees of genetic and pathophysiological
heterogeneity, irrespective of clinical manifestations. Traditional medical paradigms have …

Epilepsy is a disorder of brain networks. A better understanding of structural and dynamic
network properties may improve epilepsy diagnosis, treatment, and prognostics. Hubs are …

Numerous brain disorders demonstrate structural brain abnormalities, which are thought to
arise from molecular perturbations or connectome miswiring. The unique and shared …

Neuropsychiatric disorders are increasingly conceptualized as overlap** spectra sharing
multi-level neurobiological alterations. However, whether transdiagnostic cortical alterations …

Psychiatric disorders share neurobiology and frequently co-occur. This neurobiological and
clinical overlap highlights opportunities for transdiagnostic treatments. In this study, we used …

Through harmonized procedures and by sharing site-specific brain metrics (for example,
cortical thickness) or aggregated statistical maps, ENIGMA has set the stage for large-scale …

Functional connectivity (FC), or the statistical interdependence of blood-oxygen dependent
level (BOLD) signals between brain regions using fMRI, has emerged as a widely used tool …

Epilepsy is associated with genetic risk factors and cortico-subcortical network alterations,
but associations between neurobiological mechanisms and macroscale connectomics …

Background The pattern of structural brain abnormalities in anorexia nervosa (AN) is still not
well understood. While several studies report substantial deficits in gray matter volume and …