[HTML][HTML] Atomic force microscopy for single molecule characterisation of protein aggregation

FS Ruggeri, T Šneideris, M Vendruscolo… - Archives of biochemistry …, 2019 - Elsevier
The development of atomic force microscopy (AFM) has opened up a wide range of novel
opportunities in nanoscience and new modalities of observation in complex biological …

A novel partially open state of SHP2 points to a “multiple gear” regulation mechanism

Y Tao, J ** Single-Molecule Protein Complexes in 3D with DNA Nanoswitch Calipers
P Shrestha, D Yang, A Ward, WM Shih… - Journal of the …, 2023 - ACS Publications
The ability to accurately map the 3D geometry of single-molecule complexes in trace
samples is a challenging goal that would lead to new insights into molecular mechanics and …

Characterizing microfluidic approaches for a fast and efficient reagent exchange in single-molecule studies

J Madariaga-Marcos, R Corti, S Hormeño… - Scientific reports, 2020 - nature.com
Single-molecule experiments usually take place in flow cells. This experimental approach is
essential for experiments requiring a liquid environment, but is also useful to allow the …

CHARMM-DYES: parameterization of fluorescent dyes for use with the CHARMM force field

RA Shaw, T Johnston-Wood, B Ambrose… - Journal of Chemical …, 2020 - ACS Publications
We present CHARMM-compatible force field parameters for a series of fluorescent dyes from
the Alexa, Atto, and Cy families, commonly used in Förster resonance energy transfer …

[BOOK][B] Toward the Space-Time Limit

L Rios - 2017 - search.proquest.com
A chemical reaction is fundamentally initiated by the restructuring of a chemical bond.
Chemical reactions occur so quickly that their exact trajectory is unknown. To unlock the …

[CITATION][C] 哺乳动物单细胞研究技术的现状与未来

姜文倩, 田亚茸, 左锐, 林峻 - 生物工程学报, 2019