Breast cancer—epidemiology, classification, pathogenesis and treatment (review of literature)

B Smolarz, AZ Nowak, H Romanowicz - Cancers, 2022 - mdpi.com
Simple Summary Breast cancer is the most-commonly diagnosed malignant tumor in women
in the world, as well as the first cause of death from malignant tumors. The incidence of …

PI3K/AKT/mTOR signaling pathway in breast cancer: from molecular landscape to clinical aspects

D Miricescu, A Totan, II Stanescu-Spinu… - International journal of …, 2020 - mdpi.com
Breast cancer is a serious health problem worldwide, representing the second cause of
death through malignancies among women in developed countries. Population …

Key steps for effective breast cancer prevention

KL Britt, J Cuzick, KA Phillips - Nature Reviews Cancer, 2020 - nature.com
Despite decades of laboratory, epidemiological and clinical research, breast cancer
incidence continues to rise. Breast cancer remains the leading cancer-related cause of …

Epidemiological characteristics of and risk factors for breast cancer in the world

Z Momenimovahed, H Salehiniya - Breast Cancer: Targets and …, 2019 - Taylor & Francis
Aim Breast cancer is the most common cancer among women and one of the most important
causes of death among them. This review aimed to investigate the incidence and mortality …

[HTML][HTML] Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence

Collaborative Group on Hormonal Factors in Breast … - The Lancet, 2019 - Elsevier
Background Published findings on breast cancer risk associated with different types of
menopausal hormone therapy (MHT) are inconsistent, with limited information on long-term …

Breast cancer epidemiology and risk factors

K Rojas, A Stuckey - Clinical obstetrics and gynecology, 2016 - journals.lww.com
Between the years 2010 and 2012, the lifetime probability of develo** female breast
cancer was 12.3%, or approximately 1 in 8. Worldwide, breast cancer is the most common …

Hormone-replacement therapy: current thinking

RA Lobo - Nature Reviews Endocrinology, 2017 - nature.com
For several decades, the role of hormone-replacement therapy (HRT) has been debated.
Early observational data on HRT showed many benefits, including a reduction in coronary …

Menopausal hormone therapy and health outcomes during the intervention and extended poststop** phases of the Women's Health Initiative randomized trials

JAE Manson, RT Chlebowski, ML Stefanick… - Jama, 2013 - jamanetwork.com
Importance Menopausal hormone therapy continues in clinical use but questions remain
regarding its risks and benefits for chronic disease prevention. Objective To report a …

Hereditary breast and ovarian cancer: new genes in confined pathways

FC Nielsen, T van Overeem Hansen… - Nature Reviews …, 2016 - nature.com
Genetic abnormalities in the DNA repair genes BRCA1 and BRCA2 predispose to hereditary
breast and ovarian cancer (HBOC). However, only approximately 25% of cases of HBOC …

[HTML][HTML] Menarche, menopause, and breast cancer risk: individual participant meta-analysis, including 118 964 women with breast cancer from 117 epidemiological …

Collaborative Group on Hormonal Factors in Breast … - The lancet oncology, 2012 - Elsevier
BACKGROUND: Menarche and menopause mark the onset and cessation, respectively, of
ovarian activity associated with reproduction, and affect breast cancer risk. Our aim was to …