Since the industrial revolution, the rapid growth and development of global industries have
depended largely upon the utilization of coal-derived chemicals, and more recently, the …

Adaptive laboratory evolution (ALE) is an innovative approach for the generation of evolved
microbial strains with desired characteristics, by implementing the rules of natural selection …

Despite a steady decline in fossil resources in past few decades, demand for petroleum-
based chemicals and polymers has increased sharply. As the dead end of the petroleum …

Advanced biofuels produced by microorganisms have similar properties to petroleum-based
fuels, and can'drop in'to the existing transportation infrastructure. However, producing these …

Biofuels that are produced from biobased materials are a good alternative to petroleum
based fuels. They offer several benefits to society and the environment. Producing second …

Cruel oil or green gold is a dilemma for the oil palm industry. The oil palm industry (planting
and milling) has a devastating impact on the environment and ecosystems. Oil palm …

Efforts to improve the production of a compound of interest in Saccharomyces cerevisiae
have mainly involved engineering or overexpression of cytoplasmic enzymes. We show that …

Metabolic engineering is the enabling science of development of efficient cell factories for
the production of fuels, chemicals, pharmaceuticals, and food ingredients through microbial …

Corynebacterium glutamicum, Escherichia coli, and Saccharomyces cerevisiae in particular,
have become established as important industrial workhorses in biotechnology. Recent years …

We present here a broad overview of the field of metabolic engineering, describing in the
first section the key fundamental principles that define and distinguish it, as well as the …