Arbovirus-mosquito vector-host interactions and the impact on transmission and disease pathogenesis of arboviruses
Hundreds of viruses, designated as arboviruses, are transmitted by arthropod vectors in
complex transmission cycles between the virus, vertebrate host, and the vector. With millions …
complex transmission cycles between the virus, vertebrate host, and the vector. With millions …
Update on mosquito bite reaction: Itch and hypersensitivity, pathophysiology, prevention, and treatment
A Vander Does, A Labib, G Yosipovitch - Frontiers in immunology, 2022 - frontiersin.org
Mosquito bites are endured by most populations worldwide. Reactions to mosquito bites
range from localized wheals and papules with associated pruritus to rare systemic reactions …
range from localized wheals and papules with associated pruritus to rare systemic reactions …
High resolution proteomics of Aedes aegypti salivary glands infected with either dengue, Zika or chikungunya viruses identify new virus specific and broad antiviral …
Arboviruses such as dengue (DENV), Zika (ZIKV) and chikungunya (CHIKV) viruses infect
close to half a billion people per year, and are primarily transmitted through Aedes aegypti …
close to half a billion people per year, and are primarily transmitted through Aedes aegypti …
Safety and immunogenicity of a mosquito saliva peptide-based vaccine: a randomised, placebo-controlled, double-blind, phase 1 trial
Background In animal models, immunity to mosquito salivary proteins protects animals
against mosquito-borne disease. These findings provide a rationale to vaccinate against …
against mosquito-borne disease. These findings provide a rationale to vaccinate against …
Mosquito saliva: the hope for a universal arbovirus vaccine?
JE Manning, DM Morens, S Kamhawi… - The Journal of …, 2018 - academic.oup.com
Arthropod-borne viruses (arboviruses) are taxonomically diverse causes of significant
morbidity and mortality. In recent decades, important mosquito-borne viruses such as West …
morbidity and mortality. In recent decades, important mosquito-borne viruses such as West …
Aedes aegypti D7 Saliva Protein Inhibits Dengue Virus Infection
Aedes aegypti is the primary vector of several medically relevant arboviruses including
dengue virus (DENV) types 1–4. Ae. aegypti transmits DENV by inoculating virus-infected …
dengue virus (DENV) types 1–4. Ae. aegypti transmits DENV by inoculating virus-infected …
Inflammasome fuels dengue severity
Dengue is an acute febrile disease triggered by dengue virus. Dengue is the widespread
and rapidly transmitted mosquito-borne viral disease of humans. Diverse symptoms and …
and rapidly transmitted mosquito-borne viral disease of humans. Diverse symptoms and …
Aedes aegypti D7 long salivary proteins modulate blood feeding and parasite infection
Mosquito saliva facilitates blood meal acquisition through pharmacologically active
compounds that prevent host hemostasis and immune responses. Here, we generated two …
compounds that prevent host hemostasis and immune responses. Here, we generated two …
Re-assess vector indices threshold as an early warning tool for predicting dengue epidemic in a dengue non-endemic country
FS Chang, YT Tseng, PS Hsu, CD Chen… - PLoS neglected …, 2015 - journals.plos.org
Background Despite dengue dynamics being driven by complex interactions between
human hosts, mosquito vectors and viruses that are influenced by climate factors, an …
human hosts, mosquito vectors and viruses that are influenced by climate factors, an …
[HTML][HTML] The significance of mosquito saliva in arbovirus transmission and pathogenesis in the vertebrate host
I Visser, CJM Koenraadt, MPG Koopmans, B Rockx - One Health, 2023 - Elsevier
Due to changes in climate, numerous mosquito species are continuously extending their
geographical distributions, posing potential new public health threats as arbovirus infections …
geographical distributions, posing potential new public health threats as arbovirus infections …