Use and misuse of the gene ontology annotations

S Yon Rhee, V Wood, K Dolinski, S Draghici - Nature Reviews Genetics, 2008 - nature.com
Abstract The Gene Ontology (GO) project is a collaboration among model organism
databases to describe gene products from all organisms using a consistent and computable …

Twenty-five-year research progress in hookworm excretory/secretory products

AMI Abuzeid, X Zhou, Y Huang, G Li - Parasites & vectors, 2020 - Springer
Hookworm infection is a major public health problem that threatens about 500 million people
throughout tropical areas of the world. Adult hookworms survive for many years in the host …

[HTML][HTML] An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: proteins associated with invasion and …

MW Robinson, R Menon, SM Donnelly… - Molecular & Cellular …, 2009 - Elsevier
To infect their mammalian hosts, Fasciola hepatica larvae must penetrate and traverse the
intestinal wall of the duodenum, move through the peritoneum, and penetrate the liver. After …

[HTML][HTML] Hookworms evade host immunity by secreting a deoxyribonuclease to degrade neutrophil extracellular traps

T Bouchery, M Moyat, J Sotillo, S Silverstein, B Volpe… - Cell host & …, 2020 - cell.com
Hookworms cause a major neglected tropical disease, occurring after larvae penetrate the
host skin. Neutrophils are phagocytes that kill large pathogens by releasing neutrophil …

Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm, Ancylostoma caninum

J Mulvenna, B Hamilton, SH Nagaraj… - Molecular & Cellular …, 2009 - mcponline.org
Hookworms are blood-feeding intestinal parasites of mammalian hosts and are one of the
major human ailments affecting∼ 600 million people worldwide. These parasites form an …

Apoplastic venom allergen-like proteins of cyst nematodes modulate the activation of basal plant innate immunity by cell surface receptors

JL Lozano-Torres, RHP Wilbers, S Warmerdam… - PLoS …, 2014 - journals.plos.org
Despite causing considerable damage to host tissue during the onset of parasitism,
nematodes establish remarkably persistent infections in both animals and plants. It is …

A portrait of the “SCP/TAPS” proteins of eukaryotes—develo** a framework for fundamental research and biotechnological outcomes

C Cantacessi, BE Campbell, A Visser, P Geldhof… - Biotechnology …, 2009 - Elsevier
A wide range of proteins belonging to the SCP/TAPS “family” has been described for various
eukaryotic organisms, including plants and animals (vertebrates and invertebrates, such as …

Secreted venom allergen-like proteins of helminths: Conserved modulators of host responses in animals and plants

RHP Wilbers, R Schneiter, MHM Holterman… - PLoS …, 2018 - journals.plos.org
Despite causing considerable damage to host tissue at the onset of parasitism, invasive
helminths establish remarkably persistent infections in both animals and plants. Secretions …

Novel antiinflammatory biologics shaped by parasite–host coevolution

SM Ryan, R Ruscher, WA Johnston… - Proceedings of the …, 2022 - pnas.org
Parasitic helminth infections, while a major cause of neglected tropical disease burden,
negatively correlate with the incidence of immune-mediated inflammatory diseases such as …

The functions of CAP superfamily proteins in mammalian fertility and disease

AS Gaikwad, J Hu, DG Chapple… - Human reproduction …, 2020 - academic.oup.com
BACKGROUND Members of the cysteine-rich secretory proteins (CRISPS), antigen 5 (Ag5)
and pathogenesis-related 1 (Pr-1)(CAP) superfamily of proteins are found across the …