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Use and misuse of the gene ontology annotations
Abstract The Gene Ontology (GO) project is a collaboration among model organism
databases to describe gene products from all organisms using a consistent and computable …
databases to describe gene products from all organisms using a consistent and computable …
Twenty-five-year research progress in hookworm excretory/secretory products
AMI Abuzeid, X Zhou, Y Huang, G Li - Parasites & vectors, 2020 - Springer
Hookworm infection is a major public health problem that threatens about 500 million people
throughout tropical areas of the world. Adult hookworms survive for many years in the host …
throughout tropical areas of the world. Adult hookworms survive for many years in the host …
[HTML][HTML] An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: proteins associated with invasion and …
MW Robinson, R Menon, SM Donnelly… - Molecular & Cellular …, 2009 - Elsevier
To infect their mammalian hosts, Fasciola hepatica larvae must penetrate and traverse the
intestinal wall of the duodenum, move through the peritoneum, and penetrate the liver. After …
intestinal wall of the duodenum, move through the peritoneum, and penetrate the liver. After …
[HTML][HTML] Hookworms evade host immunity by secreting a deoxyribonuclease to degrade neutrophil extracellular traps
Hookworms cause a major neglected tropical disease, occurring after larvae penetrate the
host skin. Neutrophils are phagocytes that kill large pathogens by releasing neutrophil …
host skin. Neutrophils are phagocytes that kill large pathogens by releasing neutrophil …
Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm, Ancylostoma caninum
Hookworms are blood-feeding intestinal parasites of mammalian hosts and are one of the
major human ailments affecting∼ 600 million people worldwide. These parasites form an …
major human ailments affecting∼ 600 million people worldwide. These parasites form an …
Apoplastic venom allergen-like proteins of cyst nematodes modulate the activation of basal plant innate immunity by cell surface receptors
Despite causing considerable damage to host tissue during the onset of parasitism,
nematodes establish remarkably persistent infections in both animals and plants. It is …
nematodes establish remarkably persistent infections in both animals and plants. It is …
A portrait of the “SCP/TAPS” proteins of eukaryotes—develo** a framework for fundamental research and biotechnological outcomes
C Cantacessi, BE Campbell, A Visser, P Geldhof… - Biotechnology …, 2009 - Elsevier
A wide range of proteins belonging to the SCP/TAPS “family” has been described for various
eukaryotic organisms, including plants and animals (vertebrates and invertebrates, such as …
eukaryotic organisms, including plants and animals (vertebrates and invertebrates, such as …
Secreted venom allergen-like proteins of helminths: Conserved modulators of host responses in animals and plants
Despite causing considerable damage to host tissue at the onset of parasitism, invasive
helminths establish remarkably persistent infections in both animals and plants. Secretions …
helminths establish remarkably persistent infections in both animals and plants. Secretions …
Novel antiinflammatory biologics shaped by parasite–host coevolution
Parasitic helminth infections, while a major cause of neglected tropical disease burden,
negatively correlate with the incidence of immune-mediated inflammatory diseases such as …
negatively correlate with the incidence of immune-mediated inflammatory diseases such as …
The functions of CAP superfamily proteins in mammalian fertility and disease
BACKGROUND Members of the cysteine-rich secretory proteins (CRISPS), antigen 5 (Ag5)
and pathogenesis-related 1 (Pr-1)(CAP) superfamily of proteins are found across the …
and pathogenesis-related 1 (Pr-1)(CAP) superfamily of proteins are found across the …