Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …

Abstract Machine learning is increasingly important in microbiology where it is used for tasks
such as predicting antibiotic resistance and associating human microbiome features with …

Growing evidence suggests that the gut microbiota modulates the efficacy and toxicity of
cancer therapy, most notably immunotherapy and its immune-related adverse effects. The …

Oncogenesis is associated with intestinal dysbiosis, and stool shotgun metagenomic
sequencing in individuals with this condition might constitute a non-invasive approach for …

Background & Aims To identify gut and oral metagenomic signatures that accurately predict
pancreatic ductal carcinoma (PDAC) and to validate these signatures in independent …

The gut microbiota is crucial for human health, functioning as a complex adaptive system
akin to a vital organ. To identify core health-relevant gut microbes, we followed the systems …

Recent evidence suggests that some human cancers may harbor low-biomass microbial
ecosystems, spanning bacteria, viruses, and fungi. Bacteria, the most-studied kingdom in …

Microbes influence cancer initiation, progression and therapy responsiveness. IL-17
signaling contributes to gut barrier immunity by regulating microbes but also drives tumor …

Pancreatic cancer is a highly fatal disease, and existing treatment methods are ineffective,
so it is urgent to develop new effective treatment strategies. The high dependence of …

Recent evidence has shown that the human microbiome is associated with various
diseases, including cancer. The salivary microbiome, fecal microbiome, and circulating …