Cholangiocarcinoma (CCA) is a type of cancer with limited treatment options and a poor
prognosis. Although some important genes and pathways associated with CCA have been …

Radiotherapy is the most predominant treatment strategy for lung squamous cell carcinoma
(LUSC) patients, but radioresistance is the major obstacle to therapy effectiveness. The …

Background: Neutrophil extracellular traps (NETs) play an important role in the occurrence,
metastasis and immune escape of cancers. This study aimed to investigate NET-related …

Background Papillary thyroid carcinoma (PTC) is the most common pathological type of
thyroid cancer. The effect of traditional anti-tumor therapy is not ideal for the patients with …

The lactoferrin (LTF) gene behaves like a tumor suppressor gene in diverse tumors, such as
renal cancer, nasopharyngeal carcinoma and gastric cancer. However, the prognostic value …

Objectives Hashimoto's thyroiditis (HT) is one of the most common autoimmune disorders;
however, its underlying pathological mechanisms remain unclear. Although aberrant …

Current chemotherapeutic efficacy is limited by the rapid development of multidrug
resistance (MDR) in hepatocellular carcinoma (HCC). In this study, 66 MDR-related hub …

Aims This study aimed to investigate key regulators of aberrant iron metabolism in gliomas,
and evaluate their effect on biological functions and clinical translational relevance. Methods …

THSWD has the effect of reducing inflammation, improving microcirculation, and regulating
immune status in patients with hepatocellular carcinoma. Regardless of its clear therapeutic …

Purpose: Targeting cuproptosis is considered as a promising therapeutic strategy for the
prevention of tumors. However, the potential role of cuproptosis and its related genes in …