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[HTML][HTML] miRNA targets: from prediction tools to experimental validation
G Riolo, S Cantara, C Marzocchi, C Ricci - Methods and protocols, 2020 - mdpi.com
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression in both animals
and plants. By pairing to microRNA responsive elements (mREs) on target mRNAs, miRNAs …
and plants. By pairing to microRNA responsive elements (mREs) on target mRNAs, miRNAs …
Mechanisms of miRNA‐mediated gene regulation from common downregulation to mRNA‐specific upregulation
Discovered in 1993, micoRNAs (miRNAs) are now recognized as one of the major
regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered …
regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered …
The microRNA-200 family: small molecules with novel roles in cancer development, progression and therapy
MicroRNAs (miRNAs) are a large family of small non-coding RNAs that negatively regulate
protein-coding gene expression post-transcriptionally via base pairing between the 5 …
protein-coding gene expression post-transcriptionally via base pairing between the 5 …
[HTML][HTML] Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets
Simple Summary By the virtue of targeting multiple genes, a microRNA (miRNA) can infer
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …
[HTML][HTML] State of the art: the immunomodulatory role of MSCs for osteoarthritis
DG Kwon, MK Kim, YS Jeon, YC Nam, JS Park… - International journal of …, 2022 - mdpi.com
Osteoarthritis (OA) has generally been introduced as a degenerative disease; however, it
has recently been understood as a low-grade chronic inflammatory process that could …
has recently been understood as a low-grade chronic inflammatory process that could …
Mesenchymal stem cell-derived exosomes and MicroRNAs in cartilage regeneration: biogenesis, efficacy, miRNA enrichment and delivery
Exosomes are the small extracellular vesicles secreted by cells for intercellular
communication. Exosomes are rich in therapeutic cargos such as microRNA (miRNA), long …
communication. Exosomes are rich in therapeutic cargos such as microRNA (miRNA), long …
Placental miRNAs in feto-maternal communication mediated by extracellular vesicles
A complex network composed of at least 1900 microRNA (miRNA) species orchestrates the
development and function of the human placenta. These molecules regulate genes and …
development and function of the human placenta. These molecules regulate genes and …
MicroRNAs: not “fine-tuners” but key regulators of neuronal development and function
GM Davis, MA Haas, R Pocock - Frontiers in neurology, 2015 - frontiersin.org
MicroRNAs (miRNAs) are a class of short non-coding RNAs that operate as prominent post-
transcriptional regulators of eukaryotic gene expression. miRNAs are abundantly expressed …
transcriptional regulators of eukaryotic gene expression. miRNAs are abundantly expressed …
Selective activation of miRNAs of the primate-specific chromosome 19 miRNA cluster (C19MC) in cancer and stem cells and possible contribution to regulation of …
Background The human chromosome 19 miRNA cluster (C19MC) of 43 genes is a primate-
specific miRNA cluster that may have biological significance in the genetic complexity of the …
specific miRNA cluster that may have biological significance in the genetic complexity of the …
Sea urchin as a universal model for studies of gene networks
L Adonin, A Drozdov, NA Barlev - Frontiers in Genetics, 2021 - frontiersin.org
The purple sea urchin Strongylocentrotus purpuratus has been used for over 150 years as a
model organism in developmental biology. Using this model species, scientists have been …
model organism in developmental biology. Using this model species, scientists have been …