Therapeutic deep eutectic solvents: A comprehensive review of their thermodynamics, microstructure and drug delivery applications

MM Abdelquader, S Li, GP Andrews… - European Journal of …, 2023 - Elsevier
Deep eutectic solvents (DES) are multicomponent liquids that are usually formed by
coupling a hydrogen bond donor and acceptor leading to strong non-covalent (NC) …

Deep eutectic solvents enhancing drug solubility and its delivery

A Sharma, YR Park, A Garg, BS Lee - Journal of Medicinal …, 2024 - ACS Publications
Deep eutectic solvents (DES) are environmentally friendly solvents with the potential to
dissolve bioactive compounds without affecting their characteristics. DES has special …

Exploring the mechanism of solubilization and release of isoliquiritigenin in deep eutectic solvents

Y Hu, P Liang, Z Wang, CP Jiang, Q Zeng… - International journal of …, 2023 - Elsevier
Isoliquiritigenin (ISL) is a natural medicinal product with extensive pharmacological
activities. However, its low solubility limits its application. Therefore, this study aimed to …

Natural deep eutectic solvents (NaDES) as an emerging technology for the valorisation of natural products and agro-food residues: a review

RF González-Laredo… - … Journal of Food …, 2023 - academic.oup.com
A review paper on the natural deep eutectic solvents (NaDES) application to the extraction
of bioactives from natural products and agri-food wastes is introduced. NaDES are eutectic …

[HTML][HTML] Bioadhesive eutectogels supporting drug nanocrystals for long-acting delivery to mucosal tissues

MB Bianchi, C Zhang, E Catlin, G Sandri, M Calderón… - Materials Today Bio, 2022 - Elsevier
Eutectogels (Egels) are an emerging class of soft ionic materials outperforming traditional
temperature-intolerant hydrogels and costly ionogels. Due to their excellent elasticity, non …

Green Sorbitol-Based Deep Eutectic Solvents Enabling Near Zero-Wear of Steel–Steel Tribopairs

Q Gao, S Liu, Y Wang, K Hou, X Miao… - ACS Sustainable …, 2023 - ACS Publications
Deep eutectic solvents have emerged as promising alternatives to traditional lubricants due
to their ease of preparation, low cost, low/no pollution, reproducibility, and unique antifriction …

Exploring deep eutectic solvents for the electrochemical and chemical synthesis of photo-and electrocatalysts for hydrogen evolution

A Kityk, V Pavlik, M Hnatko - International Journal of Hydrogen Energy, 2023 - Elsevier
Hydrogen energy technologies present promising and sustainable solution to address the
imminent energy crisis. Electrochemical hydrogen production from aqueous solutions …

[HTML][HTML] Solubilization techniques used for poorly water-soluble drugs

B **e, Y Liu, X Li, P Yang, W He - Acta Pharmaceutica Sinica B, 2024 - Elsevier
Currently, about 40% of approved drugs and nearly 90% of drug candidates are poorly
water-soluble drugs. Low solubility reduces the likelihood that these drugs can be effectively …

Exploring the potential of deep eutectic solvents in pharmaceuticals: Challenges and opportunities

PA Shah, V Chavda, D Hirpara, VS Sharma… - Journal of Molecular …, 2023 - Elsevier
Deep eutectic solvents (DESs) have gained significant attention over the past twenty years
due to their versatile properties and easy preparation methods without the need for …

Assessing the compatibility of choline-based deep eutectic solvents for the structural stability and activity of cellulase: Enzyme sustain at high temperature

N Yadav, D Chahar, M Bisht, P Venkatesu - International Journal of …, 2023 - Elsevier
As a new generation of 'green solvents' deep eutectic solvents (DESs) represents a
promising alternative to the conventional solvents. Their environmental-benign nature and …