Clemastine improves emotional and social deficits in adolescent social isolation mice by reversing demyelination

D Guo, Y Yao, X Liu, Y Han - Pharmacology Biochemistry and Behavior, 2024 - Elsevier
Adolescence is a critical period for social experience-dependent oligodendrocyte maturation
and myelination. Adolescent stress predisposes to cause irreversible changes in brain …

Loss of UBE3A impacts both neuronal and non-neuronal cells in human cerebral organoids

RC Estridge, ZB Yagci, D Sen, TS Ptacek, JM Simon… - bioRxiv, 2024 - biorxiv.org
Angelman syndrome is a neurodevelopmental disorder caused by (epi) genetic lesions of
maternal UBE3A. Research has focused largely on the role of UBE3A in neurons due to its …