IgA nephropathy

E Stamellou, C Seikrit, SCW Tang, P Boor… - Nature Reviews …, 2023 - nature.com
IgA nephropathy (IgAN), the most prevalent primary glomerulonephritis worldwide, carries a
considerable lifetime risk of kidney failure. Clinical manifestations of IgAN vary from …

[HTML][HTML] Oxford classification of IgA nephropathy 2016: an update from the IgA nephropathy classification working group

H Trimarchi, J Barratt, DC Cattran, HT Cook, R Coppo… - Kidney international, 2017 - Elsevier
Since the Oxford Classification of IgA nephropathy (IgAN) was published in 2009, MEST
scores have been increasingly used in clinical practice. Further retrospective cohort studies …

KDIGO 2021 clinical practice guideline for the management of glomerular diseases

BH Rovin, SG Adler, J Barratt, F Bridoux… - Kidney …, 2021 - kidney-international.org
Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

Long-term outcomes in IgA nephropathy

D Pitcher, F Braddon, B Hendry, A Mercer… - Clinical Journal of the …, 2023 - journals.lww.com
Background IgA nephropathy can progress to kidney failure, and risk assessment soon after
diagnosis has advantages both for clinical management and the development of new …

Next-Generation Morphometry for pathomics-data mining in histopathology

DL Hölscher, N Bouteldja, M Joodaki, ML Russo… - Nature …, 2023 - nature.com
Pathology diagnostics relies on the assessment of morphology by trained experts, which
remains subjective and qualitative. Here we developed a framework for large-scale …

IgA nephropathy: an interesting autoimmune kidney disease

A Rajasekaran, BA Julian, DV Rizk - The American journal of the medical …, 2021 - Elsevier
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide. It is a leading cause of chronic kidney disease and progresses to end-stage …

Evaluating a new international risk-prediction tool in IgA nephropathy

SJ Barbour, R Coppo, H Zhang, ZH Liu… - JAMA internal …, 2019 - jamanetwork.com
Importance Although IgA nephropathy (IgAN) is the most common glomerulonephritis in the
world, there is no validated tool to predict disease progression. This limits patient-specific …

IgA nephropathy

JC Rodrigues, M Haas, HN Reich - Clinical Journal of the …, 2017 - journals.lww.com
IgA nephropathy (IgAN) is a leading cause of CKD and renal failure. Recent international
collaborative efforts have led to important discoveries that have improved our understanding …

The mucosal immune system and IgA nephropathy

L Gesualdo, V Di Leo, R Coppo - Seminars in immunopathology, 2021 - Springer
The precise pathogenesis of immunoglobulin A nephropathy (IgAN) is still not clearly
established but emerging evidence confirms a pivotal role for mucosal immunity. This review …

IgA nephropathy

KN Lai, SCW Tang, FP Schena, J Novak… - Nature reviews Disease …, 2016 - nature.com
Abstract Globally, IgA nephropathy (IgAN) is the most common primary glomerulonephritis
that can progress to renal failure. The exact pathogenesis of IgAN is not well defined, but …