[HTML][HTML] Bacterial biofilm eradication agents: a current review

AD Verderosa, M Totsika, KE Fairfull-Smith - Frontiers in chemistry, 2019 - frontiersin.org
Most free-living bacteria can attach to surfaces and aggregate to grow into multicellular
communities encased in extracellular polymeric substances called biofilms. Biofilms are …

Halogenated antimicrobial agents to combat drug-resistant pathogens

OS Faleye, BR Boya, JH Lee, I Choi, J Lee… - Pharmacological …, 2024 - Elsevier
Antimicrobial resistance presents us with a potential global crisis as it undermines the
abilities of conventional antibiotics to combat pathogenic microbes. The history of …

Bio-mimicking nano and micro-structured surface fabrication for antibacterial properties in medical implants

A Jaggessar, H Shahali, A Mathew… - Journal of …, 2017 - Springer
Orthopaedic and dental implants have become a staple of the medical industry and with an
ageing population and growing culture for active lifestyles, this trend is forecast to continue …

Natural products as inspiration for the development of bacterial antibiofilm agents

RJ Melander, AK Basak, C Melander - Natural product reports, 2020 - pubs.rsc.org
Natural products have historically been a rich source of diverse chemical matter with
numerous biological activities, and have played an important role in drug discovery in many …

Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance

B Parrino, D Schillaci, I Carnevale, E Giovannetti… - European journal of …, 2019 - Elsevier
Biofilm formation significantly contributes to microbial survival in hostile environments and it
is currently considered a key virulence factor for pathogens responsible for serious chronic …

Antimicrobial peptides derived from insects offer a novel therapeutic option to combat biofilm: A review

A Sahoo, SS Swain, A Behera, G Sahoo… - Frontiers in …, 2021 - frontiersin.org
Biofilms form a complex layer with defined structures, that attach on biotic or abiotic surfaces,
are tough to eradicate and tend to cause some resistance against most antibiotics. Several …

Novel antimicrobial 8-hydroxyquinoline-based agents: Current development, structure–activity relationships, and perspectives

AR Joaquim, MP Gionbelli, G Gosmann… - Journal of Medicinal …, 2021 - ACS Publications
The search for new antimicrobials is imperative due to the emergent resistance of new
microorganism strains. In this context, revisiting known classes like 8-hydroxyquinolines …

Quinolines and quinolones as antibacterial, antifungal, anti-virulence, antiviral and anti-parasitic agents

L Senerovic, D Opsenica, I Moric, I Aleksic… - … Infectious Diseases and …, 2020 - Springer
Infective diseases have become health threat of a global proportion due to appearance and
spread of microorganisms resistant to majority of therapeutics currently used for their …

Photochemical C− H hydroxyalkylation of quinolines and isoquinolines

B Bieszczad, LA Perego, P Melchiorre - Angewandte Chemie, 2019 - Wiley Online Library
We report herein a visible light‐mediated C− H hydroxyalkylation of quinolines and
isoquinolines that proceeds via a radical path. The process exploits the excited‐state …

Synthetic non-toxic anti-biofilm agents as a strategy in combating bacterial resistance

RM Hassan, MS Abd El-Maksoud, IAY Ghannam… - European Journal of …, 2023 - Elsevier
The tremendous increase in the bacterial resistance to the available antibiotics is a serious
problem for the treatment of various infections. Biofilm formation in bacteria significantly …