Isoxazole, constituting an important family of five-membered heterocycles with one oxygen
atom and one nitrogen atom at adjacent positions is of immense importance because of its …

Abstract Curcumin (diferuloylmethane or 1, 7-bis (4-hydroxy-3-methoxyphenyl)-1, 6-
heptadiene-3, 5-dione) is an interesting compound that is characterized by a special …

Heterocycles of the isoxazolone class stand out in the pharmaceutical field because they
have numerous biological properties, such as antioxidant, antifungal and antibacterial …

Curcumin, derived from the popular spice turmeric, is a pharmacologically active
polyphenol. Curcumin's therapeutic activity has been extensively studied in recent decades …

Abstract Curcumin [(1E, 6E)-1, 7-bis (4-hydroxy-3-methoxy-phenyl)-1, 6-heptadiene-3, 5-
dione] is a low molecular weight yellow-orange polyphenolic pigment extracted from the …

Synthesis and biological evaluation of hybrid molecules combining naturally occurring
antioxidant active structures with anti-inflammatory agents have been a strong trend in …

Isoxazoles, isoxazolines and isoxazolidines are a class of heterocyclic compounds having a
remarkable number of applications and are very versatile building blocks in organic …

Isoxazoles are five-membered aromatic heterocyclic compounds in which oxygen and
nitrogen atoms are present at positions 1 and 2 of the ring system. Isoxazole derivatives play …

A doença de Alzheimer representa cerca de 60 a 80% dos casos de demência afetando
principalmente indivíduos com idades superiores a 65 anos. Esta patologia é caracterizada …