Stroke, characterized as a neurological deficit of cerebrovascular cause, is very common in
older adults. Increasing evidence suggests stroke contributes to the risk and severity of …

This scientific statement presents a conceptual framework for the pathophysiology of post–
cardiac arrest brain injury, explores reasons for previous failure to translate preclinical data …

The gut microbiome interacts with the brain bidirectionally through the microbiome-gut-brain
axis, which plays a key role in regulating various nervous system pathophysiological …

Abstract Introduction DL-3-n-butylphthalide (NBP) and edaravone dexborneol (Eda-Dex) are
two promising reagents for stroke treatment. However, the impacts of NBP and Eda-Dex on …

Cerebral ischemic stroke is one of the leading causes of adult disability worldwide.
Reperfusion is the only therapeutic option with a lot of side effects. In the current study, we …

Enriched environment (EE) with a complex combination of sensorimotor, cognitive and
social stimulations has been shown to enhance brain plasticity and improve recovery of …

Background Chronic cerebral hypoperfusion (CCH) is a frequently observed underlying
pathology of both Alzheimer's disease (AD) and vascular dementia (VD), which is a common …

Background and purpose We focused on the, yet undescribed, therapy effect of the stable
gastric pentadecapeptide BPC 157 in hippocampal ischemia/reperfusion injuries, after …

ABSTRACT A systematic review and meta-analysis based on randomized controlled trials
(RCTs) from the last 10 years was conducted to identify the effect of computer-based training …

Alzheimer's disease (AD; progressive neurodegenerative disorder) is associated with
cognitive and functional impairment with accompanying neuropsychiatric symptoms. The …