[HTML][HTML] Ultrasmall gold nanoparticles in cancer diagnosis and therapy

M Fan, Y Han, S Gao, H Yan, L Cao, Z Li, XJ Liang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Due to their lower systemic toxicity, faster kidney clearance and higher tumor accumulation,
ultrasmall gold nanoparticles (less than 10 nm in diameter) have been proved to be …

Monodisperse gold nanoparticles: A review on synthesis and their application in modern medicine

MA Dheyab, AA Aziz, P Moradi Khaniabadi… - International Journal of …, 2022 - mdpi.com
Gold nanoparticles (AuNPs) are becoming increasingly popular as drug carriers due to their
unique properties such as size tenability, multivalency, low toxicity and biocompatibility …

Inorganic nanoparticles applied for active targeted photodynamic therapy of breast cancer

H Montaseri, CA Kruger, H Abrahamse - Pharmaceutics, 2021 - mdpi.com
Photodynamic therapy (PDT) is an alternative modality to conventional cancer treatment,
whereby a specific wavelength of light is applied to a targeted tumor, which has either a …

Injectable nano drug delivery systems for the treatment of breast cancer

U Kafle, S Agrawal, AK Dash - Pharmaceutics, 2022 - mdpi.com
Breast cancer is the most diagnosed type of cancer, with 2.26 million cases and 685,000
deaths recorded in 2020. If left untreated, this deadly disease can metastasize to distant …

Photosensitizer antibody–drug conjugates: past, present, and future

J Sandland, RW Boyle - Bioconjugate chemistry, 2019 - ACS Publications
This Review aims to highlight key aspects of tetrapyrrole-based antibody–drug conjugates
(ADCs) and significant developments in the field since 2010. Many new conjugation …

Water soluble, multifunctional antibody-porphyrin gold nanoparticles for targeted photodynamic therapy

O Penon, MJ Marín, DA Russell… - Journal of colloid and …, 2017 - Elsevier
Photodynamic therapy (PDT) is a treatment of cancer by which tumour cells are destroyed
using reactive oxygen species produced by photosensitizers following activation with visible …

Carbon dots@ platinum porphyrin composite as theranostic nanoagent for efficient photodynamic cancer therapy

F Wu, L Yue, H Su, K Wang, L Yang, X Zhu - Nanoscale Research Letters, 2018 - Springer
Photosensitizers are light-sensitive molecules that are highly hydrophobic, which poses a
challenge to their use for photodynamic therapy. Hence, considerable efforts have been …

A porphyrin-based metal–organic framework as a pH-responsive drug carrier

W Lin, Q Hu, K Jiang, Y Yang, Y Yang, Y Cui… - Journal of Solid State …, 2016 - Elsevier
A low cytotoxic porphyrin-based metal–organic framework (MOF) PCN-221, which exhibited
high PC12 cell viability via 3-(4, 5-dimethylthiazol-2-yl)− 2, 5-diphenyl tetrazolium (MTT) …

Iron oxide nanoparticles functionalized with novel hydrophobic and hydrophilic porphyrins as potential agents for photodynamic therapy

O Penon, MJ Marín, DB Amabilino, DA Russell… - Journal of colloid and …, 2016 - Elsevier
The preparation of novel porphyrin derivatives and their immobilization onto iron oxide
nanoparticles to build up suitable nanotools for potential use in photodynamic therapy (PDT) …

Applications of functionalized nanomaterials in photodynamic therapy

OJ Fakayode, N Tsolekile, SP Songca… - Biophysical reviews, 2018 - Springer
Specially designed functionalized nanomaterials such as superparamagnetic iron oxide,
gold, quantum dots and up-and down-conversion lanthanide series nanoparticles have …