The Poisson distribution and beyond: methods for microfluidic droplet production and single cell encapsulation

DJ Collins, A Neild, A DeMello, AQ Liu, Y Ai - Lab on a Chip, 2015 - pubs.rsc.org
There is a recognized and growing need for rapid and efficient cell assays, where the size of
microfluidic devices lend themselves to the manipulation of cellular populations down to the …

Droplet microfluidics: A tool for biology, chemistry and nanotechnology

S Mashaghi, A Abbaspourrad, DA Weitz… - TrAC Trends in …, 2016 - Elsevier
The ability to perform laboratory operations on small scales using miniaturized devices
provides numerous benefits, including reduced quantities of reagents and waste as well as …

Active droplet sorting in microfluidics: a review

HD **, H Zheng, W Guo, AM Gañán-Calvo, Y Ai… - Lab on a Chip, 2017 - pubs.rsc.org
The ability to manipulate and sort droplets is a fundamental issue in droplet-based
microfluidics. Various lab-on-a-chip applications can only be realized if droplets are …

Droplet microfluidics for microbiology: techniques, applications and challenges

TS Kaminski, O Scheler, P Garstecki - Lab on a Chip, 2016 - pubs.rsc.org
Droplet microfluidics has rapidly emerged as one of the key technologies opening up new
experimental possibilities in microbiology. The ability to generate, manipulate and monitor …

Mass activated droplet sorting (mads) enables high‐throughput screening of enzymatic reactions at nanoliter scale

DA Holland‐Moritz, MK Wismer… - Angewandte Chemie …, 2020 - Wiley Online Library
Microfluidic droplet sorting enables the high‐throughput screening and selection of water‐in‐
oil microreactors at speeds and volumes unparalleled by traditional well‐plate approaches …

Droplet-based high-throughput cultivation for accurate screening of antibiotic resistant gut microbes

WJ Watterson, M Tanyeri, AR Watson, CM Cham… - Elife, 2020 - elifesciences.org
Traditional cultivation approaches in microbiology are labor-intensive, low-throughput, and
yield biased sampling of environmental microbes due to ecological and evolutionary factors …

Antibiotic drug discovery

W Wohlleben, Y Mast, E Stegmann… - Microbial …, 2016 - Wiley Online Library
Due to the threat posed by the increase of highly resistant pathogenic bacteria, there is an
urgent need for new antibiotics; all the more so since in the last 20 years, the approval for …

Microfluidics for antibiotic susceptibility testing

W Postek, N Pacocha, P Garstecki - Lab on a Chip, 2022 - pubs.rsc.org
The rise of antibiotic resistance is a threat to global health. Rapid and comprehensive
analysis of infectious strains is critical to reducing the global use of antibiotics, as informed …

Recent advances in applications of droplet microfluidics

WL Chou, PY Lee, CL Yang, WY Huang, YS Lin - Micromachines, 2015 - mdpi.com
Droplet-based microfluidics is a colloidal and interfacial system that has rapidly progressed
in the past decade because of the advantages of low fabrication costs, small sample …

Image-based single cell sorting automation in droplet microfluidics

M Sesen, G Whyte - Scientific reports, 2020 - nature.com
The recent boom in single-cell omics has brought researchers one step closer to
understanding the biological mechanisms associated with cell heterogeneity. Rare cells that …