Roles of the microbiota of the female reproductive tract in gynecological and reproductive health

B Zhu, Z Tao, L Edupuganti, MG Serrano… - … and Molecular Biology …, 2022 - journals.asm.org
The microbiome of the female reproductive tract defies the convention that high biodiversity
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …

Chorioamnionitis and neonatal outcomes

VG Jain, KA Willis, A Jobe, N Ambalavanan - Pediatric research, 2022 - nature.com
Chorioamnionitis or intrauterine inflammation is a frequent cause of preterm birth.
Chorioamnionitis can affect almost every organ of the develo** fetus. Multiple microbes …

The placental membrane microbiome is altered among subjects with spontaneous preterm birth with and without chorioamnionitis

AL Prince, J Ma, PS Kannan, M Alvarez… - American journal of …, 2016 - Elsevier
Background Preterm birth (PTB) is a leading cause of neonatal morbidity and mortality and
is not uncommonly associated with chorioamnionitis. We recently have demonstrated that …

Vaginal microbiomes associated with aerobic vaginitis and bacterial vaginosis

E Kaambo, C Africa, R Chambuso… - Frontiers in public …, 2018 - frontiersin.org
A healthy vaginal microbiota is considered to be significant for maintaining vaginal health
and preventing infections. However, certain vaginal bacterial commensal species serve an …

Perinatal group B streptococcal infections: virulence factors, immunity, and prevention strategies

J Vornhagen, KMA Waldorf, L Rajagopal - Trends in microbiology, 2017 - cell.com
Group B streptococcus (GBS) or Streptococcus agalactiae is a β-hemolytic, Gram-positive
bacterium that is a leading cause of neonatal infections. GBS commonly colonizes the lower …

The pregnancy microbiome and preterm birth

E Bayar, PR Bennett, D Chan, L Sykes… - Seminars in …, 2020 - Springer
Preterm birth is a global health concern and continues to contribute to substantial neonatal
morbidity and mortality despite advances in obstetric and neonatal care. The underlying …

The double life of group B Streptococcus: asymptomatic colonizer and potent pathogen

B Armistead, E Oler, KA Waldorf, L Rajagopal - Journal of molecular biology, 2019 - Elsevier
Group B streptococcus (GBS) is a β-hemolytic gram-positive bacterium that colonizes the
lower genital tract of approximately 18% of women globally as an asymptomatic member of …

Group B streptococcal maternal colonization and neonatal disease: molecular mechanisms and preventative approaches

KA Patras, V Nizet - Frontiers in pediatrics, 2018 - frontiersin.org
Group B Streptococcus (GBS) colonizes the gastrointestinal and vaginal epithelium of a
significant percentage of healthy women, with potential for ascending intrauterine infection …

Intrauterine infection, immune system and premature birth

FR Helmo, EAR Alves, RAA Moreira… - The journal of …, 2018 - Taylor & Francis
Preterm birth accounts for nearly one million deaths among children under five years of age,
and although its etiopathogenesis is not fully elucidated, ascending intrauterine infection …

Immunobiology of acute chorioamnionitis

M Cappelletti, P Presicce, SG Kallapur - Frontiers in immunology, 2020 - frontiersin.org
Acute chorioamnionitis is characterized by neutrophilic infiltration and inflammation at the
maternal fetal interface. It is a relatively common complication of pregnancy and can have …