Effects of GH/IGF axis on bone and cartilage
Growth hormone (GH) and its mediator, the insulin-like growth factor-1 (IGF-1) regulate
somatic growth, metabolism and many aspects of aging. As such, actions of GH/IGF have …
somatic growth, metabolism and many aspects of aging. As such, actions of GH/IGF have …
Characterization of bone marrow-derived mesenchymal stem cells in aging
N Baker, LB Boyette, RS Tuan - Bone, 2015 - Elsevier
Adult mesenchymal stem cells are a resource for autologous and allogeneic cell therapies
for immune-modulation and regenerative medicine. However, patients most in need of such …
for immune-modulation and regenerative medicine. However, patients most in need of such …
Hyaluronan as a therapeutic target in human diseases
Accumulation and turnover of extracellular matrix is a hallmark of tissue injury, repair and
remodeling in human diseases. Hyaluronan is a major component of the extracellular matrix …
remodeling in human diseases. Hyaluronan is a major component of the extracellular matrix …
[BOOK][B] Tissue and organ regeneration in adults: extension of the paradigm to several organs
IV Yannas - 2014 - books.google.com
This textbook describes the basic principles of induced organ regeneration in skin and
peripheral nerves and extends the original successful paradigm to other organs. A set of …
peripheral nerves and extends the original successful paradigm to other organs. A set of …
A high resolution atlas of gene expression in the domestic sheep (Ovis aries)
Sheep are a key source of meat, milk and fibre for the global livestock sector, and an
important biomedical model. Global analysis of gene expression across multiple tissues has …
important biomedical model. Global analysis of gene expression across multiple tissues has …
CD73 regulates stemness and epithelial-mesenchymal transition in ovarian cancer-initiating cells
M Lupia, F Angiolini, G Bertalot, S Freddi… - Stem cell reports, 2018 - cell.com
Cancer-initiating cells (CICs) have been implicated in tumor development and
aggressiveness. In ovarian carcinoma (OC), CICs drive tumor formation, dissemination, and …
aggressiveness. In ovarian carcinoma (OC), CICs drive tumor formation, dissemination, and …
Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes
R Gomez-Casal, C Bhattacharya, N Ganesh, L Bailey… - Molecular cancer, 2013 - Springer
Ionizing radiation (IR) is used for patients diagnosed with unresectable non small cell lung
cancer (NSCLC), however radiotherapy remains largely palliative due to radioresistance …
cancer (NSCLC), however radiotherapy remains largely palliative due to radioresistance …
Nomenclature and heterogeneity: consequences for the use of mesenchymal stem cells in regenerative medicine
A Wilson, A Webster, P Genever - Regenerative Medicine, 2019 - Taylor & Francis
Mesenchymal stem cells (MSCs) are in development for many clinical indications, based
both on 'stem'properties (tissue repair or regeneration) and on signaling repertoire …
both on 'stem'properties (tissue repair or regeneration) and on signaling repertoire …
Comprehensive transcriptomic and proteomic characterization of human mesenchymal stem cells reveals source specific cellular markers
AM Billing, H Ben Hamidane, SS Dib, RJ Cotton… - Scientific reports, 2016 - nature.com
Mesenchymal stem cells (MSC) are multipotent cells with great potential in therapy, reflected
by more than 500 MSC-based clinical trials registered with the NIH. MSC are derived from …
by more than 500 MSC-based clinical trials registered with the NIH. MSC are derived from …
Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI)
PW Andrews, D Baker, N Benvinisty… - Regenerative …, 2015 - Taylor & Francis
In 2009 the International Stem Cell Banking Initiative (ISCBI) contributors and the Ethics
Working Party of the International Stem Cell Forum published a consensus on principles of …
Working Party of the International Stem Cell Forum published a consensus on principles of …