The clinical course of cirrhosis is mostly determined by the progressive increase of portal
hypertension, hyperdynamic circulation, bacterial translocation and activation of systemic …

Objectives To summarise the evidence and evaluate the validity of the associations between
type 2 diabetes and the risk of develo** or dying from cancer. Design An umbrella review …

There is a pressing need for allogeneic chimeric antigen receptor (CAR)-immune cell
therapies that are safe, effective and affordable. We conducted a phase 1/2 trial of cord …

Importance Preventive interventions are needed to protect residents and staff of skilled
nursing and assisted living facilities from COVID-19 during outbreaks in their facilities …

PURPOSE Limitations of the paclitaxel-doxorubicin-cisplatin (TAP) regimen in the treatment
of endometrial cancer include tolerability and cumbersome scheduling. The Gynecologic …

Background Type 1 diabetes is a chronic autoimmune disease that leads to destruction of
insulin-producing beta cells and dependence on exogenous insulin for survival. Some …

Background Observational studies support an association between a low blood 25-
hydroxyvitamin D level and the risk of type 2 diabetes. However, whether vitamin D …

Importance Concurrent chemoradiotherapy has been the standard treatment for stage II
nasopharyngeal carcinoma (NPC) based on data using 2-dimensional conventional …

Im Juni 2019 ist Prof. Lothar Sachs verstorben, ein Wegbereiter und Mentor für die
Anwendung statistischer Methoden in zahlreichen Gebieten. Er wurde 1929 in Berlin …

Survival analysis, or more generally, time-to-event analysis, refers to a set of methods for
analyzing the length of time until the occurrence of a well-defined end point of interest. A …