DNA nanotechnology assisted nanopore-based analysis
Nanopore technology is a promising label-free detection method. However, challenges exist
for its further application in sequencing, clinical diagnostics and ultra-sensitive single …
for its further application in sequencing, clinical diagnostics and ultra-sensitive single …
Functional aqueous droplet networks
Droplet interface bilayers (DIBs), comprising individual lipid bilayers between pairs of
aqueous droplets in an oil, are proving to be a useful tool for studying membrane proteins …
aqueous droplets in an oil, are proving to be a useful tool for studying membrane proteins …
Signalling and differentiation in emulsion-based multi-compartmentalized in vitro gene circuits
Multicellularity enables the growth of complex life forms as it allows for the specialization of
cell types, differentiation and large-scale spatial organization. In a similar way, modular …
cell types, differentiation and large-scale spatial organization. In a similar way, modular …
Programmable DNA-based Boolean logic microfluidic processing unit
As molecular computing materials, information-encoded deoxyribonucleic acid (DNA)
strands provide a logical computing process by cascaded and parallel chain reactions …
strands provide a logical computing process by cascaded and parallel chain reactions …
Light-patterning of synthetic tissues with single droplet resolution
Synthetic tissues can be generated by forming networks of aqueous droplets in lipid-
containing oil. Each droplet contains a cell-free expression system and is connected to its …
containing oil. Each droplet contains a cell-free expression system and is connected to its …
Harnessing DNA computing and nanopore decoding for practical applications: from informatics to microRNA-targeting diagnostics
S Takiguchi, N Takeuchi, V Shenshin… - Chemical Society …, 2024 - pubs.rsc.org
DNA computing represents a subfield of molecular computing with the potential to become a
significant area of next-generation computation due to the high programmability inherent in …
significant area of next-generation computation due to the high programmability inherent in …
Pattern recognition of microRNA expression in body fluids using nanopore decoding at subfemtomolar concentrations
N Takeuchi, M Hiratani, R Kawano - JACS Au, 2022 - ACS Publications
This paper describes a method for detecting microRNA (miRNA) expression patterns using
the nanopore-based DNA computing technology. miRNAs have shown promise as markers …
the nanopore-based DNA computing technology. miRNAs have shown promise as markers …
Development of artificial cell models using microfluidic technology and synthetic biology
K Kamiya - Micromachines, 2020 - mdpi.com
Giant lipid vesicles or liposomes are primarily composed of phospholipids and form a lipid
bilayer structurally similar to that of the cell membrane. These vesicles, like living cells, are 5 …
bilayer structurally similar to that of the cell membrane. These vesicles, like living cells, are 5 …
DNA logic operation with nanopore decoding to recognize microRNA patterns in small cell lung cancer
M Hiratani, R Kawano - Analytical chemistry, 2018 - ACS Publications
Although DNA computation has traditionally been developed for parallel calculations in
molecular analyses, this approach has recently been considered for use in diagnostic or …
molecular analyses, this approach has recently been considered for use in diagnostic or …
Synthetic tissues
While significant advances have been achieved with non-living synthetic cells built from the
bottom-up, less progress has been made with the fabrication of synthetic tissues built from …
bottom-up, less progress has been made with the fabrication of synthetic tissues built from …