Computational repurposing of tamibarotene against triple mutant variant of SARS-CoV-2

S Mujwar - Computers in Biology and Medicine, 2021 - Elsevier
The outbreak of the triple mutant strain of severe acute respiratory syndrome coronavirus-2
(SARS-COV-2) was more virulent and pathogenic than its original strain. The viral triple …

Computational bioprospecting guggulsterone against ADP ribose phosphatase of SARS-CoV-2

M Kciuk, S Mujwar, I Rani, K Munjal, A Gielecińska… - Molecules, 2022 - mdpi.com
Coronavirus Disease-2019 (COVID-19) is a highly contagious disease caused by Severe
Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2). The World Health Organization …

Repurposing benzbromarone as antifolate to develop novel antifungal therapy for Candida albicans

S Mujwar, A Tripathi - Journal of Molecular Modeling, 2022 - Springer
Fungal infections in humans are responsible for mild to severe infections resulting in
systemic effects that cause a large amount of mortality. Invasive fungal infections are having …

[HTML][HTML] Integrated biorefinery approach to valorise Saccharina latissima biomass: Combined sustainable processing to produce biologically active fucoxanthin …

CR McElroy, L Kopanitsa, R Helmes, J Fan… - … Technology & Innovation, 2023 - Elsevier
The feasibility of European seaweed farming depends on the valorisation of algal biomass
harvested. In the present work we have combined sequential extraction processes from …

Design of novel anti-cancer drugs targeting TRKs inhibitors based 3D QSAR, molecular docking and molecular dynamics simulation

M Er-Rajy, M El Fadili, S Mujwar… - Journal of …, 2023 - Taylor & Francis
Tropomyosin receptor kinase (TRK) enzymes are responsible for different types of tumors
caused by neurotrophic tyrosine receptor kinase gene fusion and have been identified as an …

[PDF][PDF] Rifampicin as potent inhibitor of COVID-19 main protease: In-silico docking approach

H Soni, D Gautam, S Sharma… - Saudi Journal of Medical …, 2020 - saudijournals.com
Abstract Corona virus (COVID-19) is an enveloped RNA virus that is diversely initiates in
humans and wildlife. A total of 6 species have been identified to cause disease in humans …

Computational bioprospecting of andrographolide derivatives as potent cyclooxygenase-2 inhibitors

S Mujwar - Biomedical and Biotechnology Research Journal …, 2021 - journals.lww.com
Background: Inflammation is a protective response of the human body that still causes a
high level of discomfort because of the associated pain and other inflammatory reactions …

Docking based screening of curcumin derivatives: A novel approach in the inhibition of tubercular DHFR

S Mujwar, K Shah, JK Gupta… - International Journal of …, 2021 - inderscienceonline.com
Tuberculosis is one of the main causes of morbidity and mortality across the globe.
Mycobacterium tuberculosis can attack any part of the human body and can cause …

Computational design of phosphatidylinositol 3-kinase inhibitors

I Rani, A Goyal, M Sharma - ASSAY and Drug Development …, 2022 - liebertpub.com
One of the most sought-after therapeutic targets for treating human cancers is the
phosphoinositide 3-kinase; PI3k is an integral part of the PI3K/protein kinase B signaling …

Computational design and biological depiction of novel naproxen derivative

K Shah, S Mujwar, G Krishna… - ASSAY and Drug …, 2020 - liebertpub.com
Naproxen (NAP) is one of the commonly used nonselective Cycloxygenase (COX) inhibitors.
It is a choice of drug for anti-inflammatory activity by subsiding the generation of the …