Respiratory Syncytial Virus (RSV) is the commonest cause of severe respiratory infection in
infants, leading to over 3 million hospitalizations and around 66,000 deaths worldwide each …

The incidence of allergic disease continues to rise in industrialized countries. The rapid
increase in the incidence of allergic disease throughout the past half century suggests that …

Migration and homing of immune cells are critical for immune surveillance. Trafficking is
mediated by combinations of adhesion and chemokine receptors that guide immune cells, in …

Recently, the IL-17 family member cytokines have become prominent subjects of
investigation. IL-17 (IL-17A) is the best-described member of this family where its production …

Uterine life is arguably the most critical time in developmental programming, when
environmental exposures may have the greatest potential to influence evolving fetal …

Severe, steroid‐resistant asthma is clinically and economically important since affected
individuals do not respond to mainstay corticosteroid treatments for asthma. Patients with …

Background Early-life human rhinovirus infection has been linked to asthma development in
high-risk infants and children. Nevertheless, the role of rhinovirus infection in the initiation of …

Asthma is an inflammatory disorder of the airways, characterized by infiltration of mast cells,
eosinophils, and Th2-type CD4+ T cells in the airway wall. Airway epithelium constitutes the …

Respiratory syncytial virus (RSV) is a common and contagious virus that results in acute
respiratory tract infections in infants. In many cases, the symptoms of RSV remain mild …

Asthma is recognized as a heterogeneous disorder, although in most patients, the clinical
manifestations are effectively managed with established combination therapies. However, 5 …