Atomic force microscopy-based mechanobiology

M Krieg, G Fläschner, D Alsteens, BM Gaub… - Nature Reviews …, 2019‏ - nature.com
Mechanobiology emerges at the crossroads of medicine, biology, biophysics and
engineering and describes how the responses of proteins, cells, tissues and organs to …

Imaging modes of atomic force microscopy for application in molecular and cell biology

YF Dufrêne, T Ando, R Garcia, D Alsteens… - Nature …, 2017‏ - nature.com
Atomic force microscopy (AFM) is a powerful, multifunctional imaging platform that allows
biological samples, from single molecules to living cells, to be visualized and manipulated …

The emergence of multifrequency force microscopy

R Garcia, ET Herruzo - Nature nanotechnology, 2012‏ - nature.com
In atomic force microscopy a cantilever with a sharp tip attached to it is scanned over the
surface of a sample, and information about the surface is extracted by measuring how the …

Multiparametric imaging of biological systems by force-distance curve–based AFM

YF Dufrêne, D Martínez-Martín, I Medalsy, D Alsteens… - Nature …, 2013‏ - nature.com
A current challenge in the life sciences is to understand how biological systems change their
structural, biophysical and chemical properties to adjust functionality. Addressing this issue …

Atomic force microscopy-based characterization and design of biointerfaces

D Alsteens, HE Gaub, R Newton… - Nature Reviews …, 2017‏ - nature.com
Atomic force microscopy (AFM)-based methods have matured into a powerful nanoscopic
platform, enabling the characterization of a wide range of biological and synthetic …

Atomic-and molecular-resolution map** of solid–liquid interfaces by 3D atomic force microscopy

T Fukuma, R Garcia - ACS nano, 2018‏ - ACS Publications
Hydration layers are ubiquitous in life and technology. Hence, interfacial aqueous layers
have a central role in a wide range of phenomena from materials science to molecular and …

[HTML][HTML] Nanomechanical map** of soft matter by bimodal force microscopy

R Garcia, R Proksch - European Polymer Journal, 2013‏ - Elsevier
Bimodal force microscopy is a dynamic force-based method with the capability of map**
simultaneously the topography and the nanomechanical properties of soft-matter surfaces …

Fast, quantitative and high resolution map** of viscoelastic properties with bimodal AFM

S Benaglia, CA Amo, R Garcia - Nanoscale, 2019‏ - pubs.rsc.org
Quantitative map** of viscoelastic properties of soft matter with a nanoscale spatial
resolution is an active and relevant research topic in atomic force microscopy (AFM) and …

Multifrequency AFM reveals lipid membrane mechanical properties and the effect of cholesterol in modulating viscoelasticity

Z Al-Rekabi, S Contera - Proceedings of the National Academy of …, 2018‏ - pnas.org
The physical properties of lipid bilayers comprising the cell membrane occupy the current
spotlight of membrane biology. Their traditional representation as a passive 2D fluid has …

Advanced atomic force microscopies and their applications in two-dimensional materials: a review

R Xu, J Guo, S Mi, H Wen, F Pang, W Ji… - Materials …, 2022‏ - iopscience.iop.org
Scanning probe microscopy (SPM) allows the spatial imaging, measurement, and
manipulation of nano and atomic scale surfaces in real space. In the last two decades …