The physics of protein self-assembly
Understanding protein self-assembly is important for many biological and industrial
processes. Proteins can self-assemble into crystals, filaments, gels, and other amorphous …
processes. Proteins can self-assemble into crystals, filaments, gels, and other amorphous …
The synergic effect of water and biomolecules in intracellular phase separation
Phase separation has long been observed within aqueous mixtures of two or more different
compounds, such as proteins, salts, polysaccharides and synthetic polymers. A growing …
compounds, such as proteins, salts, polysaccharides and synthetic polymers. A growing …
On the distribution of protein refractive index increments
The protein refractive index increment, dn/dc, is an important parameter underlying the
concentration determination and the biophysical characterization of proteins and protein …
concentration determination and the biophysical characterization of proteins and protein …
Protein analysis by dynamic light scattering: Methods and techniques for students
Dynamic light scattering (DLS) analyses are routinely used in biology laboratories to detect
aggregates in macromolecular solutions, to determine the size of proteins, nucleic acids …
aggregates in macromolecular solutions, to determine the size of proteins, nucleic acids …
Single-shot real-time video recording of a photonic Mach cone induced by a scattered light pulse
Ultrafast video recording of spatiotemporal light distribution in a scattering medium has a
significant impact in biomedicine. Although many simulation tools have been implemented …
significant impact in biomedicine. Although many simulation tools have been implemented …
Nonspecific binding of adenosine tripolyphosphate and tripolyphosphate modulates the phase behavior of lysozyme
Adenosine tripolyphosphate (ATP) is a small polyvalent anion that has recently been shown
to interact with proteins and have a major impact on assembly processes involved in …
to interact with proteins and have a major impact on assembly processes involved in …
The role of electrostatics in protein–protein interactions of a monoclonal antibody
D Roberts, R Keeling, M Tracka… - Molecular …, 2014 - ACS Publications
Understanding how protein–protein interactions depend on the choice of buffer, salt, ionic
strength, and pH is needed to have better control over protein solution behavior. Here, we …
strength, and pH is needed to have better control over protein solution behavior. Here, we …
Assembling membraneless organelles from de novo designed proteins
AT Hilditch, A Romanyuk, SJ Cross, R Obexer… - Nature Chemistry, 2024 - nature.com
Recent advances in de novo protein design have delivered a diversity of discrete de novo
protein structures and complexes. A new challenge for the field is to use these designs …
protein structures and complexes. A new challenge for the field is to use these designs …
Cataract-associated P23T γD-crystallin retains a native-like fold in amorphous-looking aggregates formed at physiological pH
Cataracts cause vision loss through the large-scale aggregation of eye lens proteins as a
result of ageing or congenital mutations. The development of new treatments is hindered by …
result of ageing or congenital mutations. The development of new treatments is hindered by …
Theoretical and numerical study of the phase diagram of patchy colloids: Ordered and disordered patch arrangements
E Bianchi, P Tartaglia, E Zaccarelli… - The Journal of chemical …, 2008 - pubs.aip.org
We report theoretical and numerical evaluations of the phase diagram for a model of patchy
particles. Specifically, we study hard spheres whose surface is decorated by a small number …
particles. Specifically, we study hard spheres whose surface is decorated by a small number …