Digital ocular fundus imaging: a review

R Bernardes, P Serranho, C Lobo - Ophthalmologica, 2011 - karger.com
Ocular fundus imaging plays a key role in monitoring the health status of the human eye.
Currently, a large number of imaging modalities allow the assessment and/or quantification …

Targeting WNT signaling for multifaceted glioblastoma therapy

M McCord, Y Mukouyama, MR Gilbert… - Frontiers in cellular …, 2017 - frontiersin.org
The WNT signaling pathway has been of great interest to developmental biologists for
decades and has more recently become a central topic for study in cancer biology. It is vital …

Phenotypes and biomarkers of diabetic retinopathy

J Cunha-Vaz, L Ribeiro, C Lobo - Progress in retinal and eye research, 2014 - Elsevier
Diabetic retinopathy (DR) remains a major cause of blindness as the prevalence of diabetes
is expected to approximately double globally between 2000 and 2030. DR progresses over …

Wnt signaling mediates pathological vascular growth in proliferative retinopathy

J Chen, A Stahl, NM Krah, MR Seaward, RJ Dennison… - Circulation, 2011 - Am Heart Assoc
Background—Ischemic proliferative retinopathy, characterized by pathological retinal
neovascularization, is a major cause of blindness in working-age adults and children …

Microaneurysm turnover at the macula predicts risk of development of clinically significant macular edema in persons with mild nonproliferative diabetic retinopathy

ML Ribeiro, SG Nunes, JG Cunha-Vaz - Diabetes care, 2013 - Am Diabetes Assoc
OBJECTIVE To examine the relationship between microaneurysm (MA) turnover using
automated analysis of fundus photographs (RetmarkerDR; Critical Health SA) and …

Microaneurysm turnover is a biomarker for diabetic retinopathy progression to clinically significant macular edema: findings for type 2 diabetics with nonproliferative …

S Nunes, I Pires, A Rosa, L Duarte, R Bernardes… - …, 2009 - karger.com
Purpose: To examine the relationship between microaneurysm turnover (formation rate),
using a new semi-automatic method (MA-Tracker) based on color fundus photographs, and …

The relationship of macular thickness to clinically graded diabetic retinopathy severity in eyes without clinically detected diabetic macular edema

DJ Browning, CM Fraser, S Clark - Ophthalmology, 2008 - Elsevier
PURPOSE: To examine the relationship of optical coherence tomography (OCT) measured
macular thickness to retinopathy severity in patients with diabetes and no clinically …

Effect of calcium dobesilate on progression of early diabetic retinopathy: a randomised double-blind study

ML Ribeiro, AI Seres, AM Carneiro, M Stur… - Graefe's archive for …, 2006 - Springer
Background The study was carried out to confirm the effect of calcium dobesilate (CaD)
compared to placebo (PLA) on the blood-retinal barrier (BRB) permeability in early diabetic …

Diabetes downregulates presynaptic proteins and reduces basal synapsin I phosphorylation in rat retina

HD VanGuilder, RM Brucklacher, K Patel… - European Journal of …, 2008 - Wiley Online Library
Diabetic retinopathy can result in vision loss and involves progressive neurovascular
degeneration of the retina. This study tested the hypothesis that diabetes decreases the …

The value of glycosylated hemoglobin in the diagnosis of diabetic retinopathy: a systematic review and Meta-analysis

B Zhang, B Zhang, Z Zhou, Y Guo, D Wang - BMC Endocrine Disorders, 2021 - Springer
Abstract Objective Glycosylated hemoglobin (HbA1c) has obvious clinical value in the
diagnosis of diabetes, but the conclusions on the diagnostic value of diabetic retinopathy …