Modern approaches for evaluating treatment effect heterogeneity from clinical trials and observational data

I Lipkovich, D Svensson, B Ratitch… - Statistics in …, 2024 - Wiley Online Library
In this paper, we review recent advances in statistical methods for the evaluation of the
heterogeneity of treatment effects (HTE), including subgroup identification and estimation of …

Learning optimal group-structured individualized treatment rules with many treatments

H Ma, D Zeng, Y Liu - Journal of Machine Learning Research, 2023 - jmlr.org
Data driven individualized decision making problems have received a lot of attentions in
recent years. In particular, decision makers aim to determine the optimal Individualized …

Learning optimal distributionally robust individualized treatment rules

W Mo, Z Qi, Y Liu - Journal of the American Statistical Association, 2021 - Taylor & Francis
Recent development in the data-driven decision science has seen great advances in
individualized decision making. Given data with individual covariates, treatment …

Learning individualized treatment rules with many treatments: A supervised clustering approach using adaptive fusion

H Ma, D Zeng, Y Liu - Advances in Neural Information …, 2022 - proceedings.neurips.cc
Abstract Learning an optimal Individualized Treatment Rule (ITR) is a very important
problem in precision medicine. This paper is concerned with the challenge when the …

[BOOK][B] Real world health care data analysis: causal methods and implementation using SAS

D Faries, X Zhang, Z Kadziola, U Siebert, F Kuehne… - 2020 - books.google.com
Discover best practices for real world data research with SAS code and examples Real
world health care data is common and growing in use with sources such as observational …

Efficient learning of optimal individualized treatment rules for heteroscedastic or misspecified treatment-free effect models

W Mo, Y Liu - Journal of the Royal Statistical Society Series B …, 2022 - academic.oup.com
Recent development in data-driven decision science has seen great advances in
individualized decision making. Given data with individual covariates, treatment …

Optimal individualized treatment rule for combination treatments under budget constraints

Q Xu, H Fu, A Qu - Journal of the Royal Statistical Society Series …, 2024 - academic.oup.com
The individualized treatment rule (ITR), which recommends an optimal treatment based on
individual characteristics, has drawn considerable interest from many areas such as …

Multi-label residual weighted learning for individualized combination treatment rule

Q Xu, X Cao, G Chen, H Zeng, H Fu… - Electronic Journal of …, 2024 - projecteuclid.org
Individualized treatment rules (ITRs) have been widely applied in many fields such as
precision medicine and personalized marketing. Beyond the extensive studies on ITR for …

Estimating individualized optimal combination therapies through outcome weighted deep learning algorithms

M Liang, T Ye, H Fu - Statistics in medicine, 2018 - Wiley Online Library
With the advancement in drug development, multiple treatments are available for a single
disease. Patients can often benefit from taking multiple treatments simultaneously. For …

Multicategory angle-based learning for estimating optimal dynamic treatment regimes with censored data

F Xue, Y Zhang, W Zhou, H Fu, A Qu - Journal of the American …, 2022 - Taylor & Francis
An optimal dynamic treatment regime (DTR) consists of a sequence of decision rules in
maximizing long-term benefits, which is applicable for chronic diseases such as HIV …