Genetic Functionalization of Protein-Based Biomaterials via Protein Fusions

GG Mendes, B Faulk, B Kaparthi, AR Irion… - …, 2024 - ACS Publications
Proteins implement many useful functions, including binding ligands with unparalleled
affinity and specificity, catalyzing stereospecific chemical reactions, and directing cell …

Chemical and temporal manipulation of early steps in protein assembly tunes the structure and intermolecular interactions of protein‐based materials

V Italia, A Jons, B Kaparthi, B Faulk… - Protein …, 2025 - Wiley Online Library
The Drosophila intrinsically disordered protein Ultrabithorax (Ubx) undergoes a series of
phase transitions, beginning with noncovalent interactions between apparently randomly …

Identification of Multiple Dityrosine Bonds in Materials Composed of the Drosophila Protein Ultrabithorax

DW Howell, SP Tsai, K Churion… - Advanced functional …, 2015 - Wiley Online Library
The recombinant protein Ultrabithorax (Ubx), a Drosophila melanogaster Hox transcription
factor, self‐assembles in vitro into biocompatible materials that are remarkably extensible …

Functionalization of ultrabithorax materials with vascular endothelial growth factor enhances angiogenic activity

DW Howell, CL Duran, SP Tsai, SE Bondos… - …, 2016 - ACS Publications
Successful design of tissue engineering scaffolds must include the ability to stimulate
vascular development by incorporating angiogenic growth factors. Current approaches can …

The Effect of Protein Fusions on the Production and Mechanical Properties of Protein‐Based Materials

SP Tsai, DW Howell, Z Huang, HC Hsiao… - Advanced Functional …, 2015 - Wiley Online Library
Proteins implement most of the vital molecular functions of living organisms, including
structural support, energy generation, biomolecule sensing, and chemical catalysis, storage …

Materials composed of the Drosophila Hox protein Ultrabithorax are biocompatible and nonimmunogenic

JL Patterson, AM Arenas‐Gamboa… - … Research Part A, 2015 - Wiley Online Library
Although the in vivo function of the Drosophila melanogaster Hox protein Ultrabithorax (Ubx)
is to regulate transcription, in vitro Ubx hierarchically self‐assembles to form nanoscale to …

Generating Novel Materials Using the Intrinsically Disordered Protein Ubx

GG Mendes, RM Booth, DL Pattison, AJ Alvarez… - Methods in …, 2018 - Elsevier
The development of functionalized materials is needed to enable diverse applications.
Protein-based materials are typically biocompatible and biodegradable and can exhibit a …

Culture of Tumorigenic Cells on Protein Fibers Reveals Metastatic Cell Behaviors

HC Hsiao, A Santos, DW Howell, JL Patterson… - …, 2016 - ACS Publications
Tumorigenic cell behaviors can be suppressed or enhanced by their physicochemical
environment. As a first step toward develo** materials that allow tumorigenic behaviors to …

[PDF][PDF] Valeria ITALIA

MJ PETERS - 2022 - core.ac.uk
Protein-based materials are currently the subject of intense research interest since they
have an extended range of potential applications, such as improved bio-membrane …

Understanding novel protein-derived biopolymers to enable biomimetic devices

V Italia - 2021 - theses.hal.science
Protein-based materials are currently the subject of intense research interest since they
have an extended range of potential applications, such as improved bio-membrane …