Nanotechnology in pharmaceutical and biomedical applications: Dendrimers

P SZYMAŃSKI, M Markowicz, E MIKICIUK-OLASIK - Nano, 2011 - World Scientific
Nanotechnology, a separate field of knowledge since 1980s, involves utilization of
nanomaterials not only in electronics and catalysis, but also in biomedical research …

Interactions of dendrimers with biological drug targets: reality or mystery–a gap in drug delivery and development research

S Ahmed, SB Vepuri, RS Kalhapure… - Biomaterials science, 2016 - pubs.rsc.org
Dendrimers have emerged as novel and efficient materials that can be used as therapeutic
agents/drugs or as drug delivery carriers to enhance therapeutic outcomes. Molecular …

Investigation of host-guest interactions between polyester dendrimers and ibuprofen using density functional theory (DFT)

S Bazyari-Delavar, F Badalkhani-Khamseh… - Computational and …, 2020 - Elsevier
Polyester dendrimers are mostly non-toxic and this advantage besides biodegradability
gives them a great chance of success in the field of drug delivery. This study investigates …

Study of interaction energies between the PAMAM dendrimer and nonsteroidal anti-inflammatory drug using a distributed computational strategy and experimental …

F Avila-Salas, C Sandoval, J Caballero… - The Journal of …, 2012 - ACS Publications
The structure of a dendrimer exhibits a large number of internal and superficial cavities,
which can be exploited, to capture and deliver small organic molecules, enabling their use …

Pharmacoinformatic approaches to understand complexation of dendrimeric nanoparticles with drugs

V Jain, PV Bharatam - Nanoscale, 2014 - pubs.rsc.org
Nanoparticle based drug delivery systems are gaining popularity due to their wide spectrum
advantages over traditional drug delivery systems; among them, dendrimeric nano-vectors …

Atomistic computer simulations on multi-loaded PAMAM dendrimers: A comparison of amine-and hydroxyl-terminated dendrimers

F Badalkhani-Khamseh, A Ebrahim-Habibi… - Journal of computer …, 2017 - Springer
Abstract Poly (amidoamine)(PAMAM) dendrimers have been extensively studied as delivery
vectors in biomedical applications. A limited number of molecular dynamics (MD) simulation …

DFT computational investigation of the reaction behavior of polyamidoamine dendrimer as nanocarrier for delivery of melphalan anticancer drug

E Ehsani, F Shojaie - Journal of Molecular Liquids, 2021 - Elsevier
In this research, a theoretical study on the structural properties and reactivity of the
Melphalan anticancer drug with G0 polyamidoamine dendrimer is provided in both phases …

Fluidized or not fluidized? Biophysical characterization of biohybrid lipid/protein/polymer liposomes and their interaction with tetracaine

R Pérez-Isidoro, FJ Guevara-Pantoja… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Background Nanomedicine and the pharmaceutical industry demand the investigation of
new biomaterials to improve drug therapies. Combinations of lipids, proteins, and polymers …

Complexation of nicotinic acid with first generation poly (amidoamine) dendrimers: A microscopic view from density functional theory

F Badalkhani-Khamseh, A Bahrami… - Chemical Physics …, 2017 - Elsevier
This study explains some electronic and structural parameters of niacin (NA) encapsulation
into PAMAM-G1 dendrimer using DFT calculations. Optimized structural geometries …

Molecular simulation study of PAMAM dendrimer composite membranes

S Amjad-Iranagh, K Golzar, H Modarress - Journal of molecular modeling, 2014 - Springer
Pure polysulfone (PSF) and its composites with chitosan (CST), hyaluronic acid (HA),
conventional poly (amidoamine), and hydroxyl poly (amidoamine) dendrimers as the …