Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

The vascular endothelial growth factor (VEGF) family, the regulator of blood and lymphatic
vessels, is mostly investigated in the tumor and ophthalmic field. However, the functions it …

Blood and lymphatic vessels pervade almost all body tissues and have numerous essential
roles in physiology and disease. The inner lining of these networks is formed by a single …

Vascular endothelial growth factors (VEGFs) are best known for their involvement in
orchestrating the development and maintenance of the blood and lymphatic vascular …

Higher organisms rely on a closed cardiovascular circulatory system with blood vessels
supplying vital nutrients and oxygen to distant tissues. Not surprisingly, vascular pathologies …

Five vascular endothelial growth factor receptor (VEGFR) ligands (VEGF-A,-B,–C,-D, and
placental growth factor [PlGF]) constitute the VEGF family. VEGF-A binds VEGF receptors 1 …

Excess dietary lipid uptake causes obesity, a major global health problem. Enterocyte-
absorbed lipids are packaged into chylomicrons, which enter the bloodstream through …

The crosstalk between endothelial cells and cardiomyocytes has emerged as a requisite for
normal cardiac development, but also a key pathogenic player during the onset and …

The heterocellular nature of the heart has been receiving increasing attention in recent
years. In addition to cardiomyocytes as the prototypical cell type of the heart, non-myocytes …

The heart is a complex organ consisting of various cell types, each of which plays an
important role in both physiological and pathophysiological conditions. The cells …