Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …
nanomedicine and may significantly impact the future of healthcare. However, the clinical …
[HTML][HTML] Engineered nanoparticles interacting with cells: size matters
With the rapid advancement of nanoscience and nanotechnology, detailed knowledge of
interactions between engineered nanomaterials and cells, tissues and organisms has …
interactions between engineered nanomaterials and cells, tissues and organisms has …
Barriers, pathways and processes for uptake, translocation and accumulation of nanomaterials in plants–Critical review
Uptake, transport and toxicity of engineered nanomaterials (ENMs) into plant cells are
complex processes that are currently still not well understood. Parts of this problem are the …
complex processes that are currently still not well understood. Parts of this problem are the …
Nanoparticle size effects in biomedical applications
Nanoparticle size plays a central role in determining material properties and performance in
biomedical applications. A wide variety of functional nanomaterials and nano-bioconjugates …
biomedical applications. A wide variety of functional nanomaterials and nano-bioconjugates …
Converting nanotoxicity data to information using artificial intelligence and simulation
Decades of nanotoxicology research have generated extensive and diverse data sets.
However, data is not equal to information. The question is how to extract critical information …
However, data is not equal to information. The question is how to extract critical information …
[HTML][HTML] Exploration and insights into the cellular internalization and intracellular fate of amphiphilic polymeric nanocarriers
The beneficial or deleterious effects of nanomedicines emerge from their complex
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …
The interplay of size and surface functionality on the cellular uptake of sub-10 nm gold nanoparticles
Correlation of the surface physicochemical properties of nanoparticles with their interactions
with biosystems provides key foundational data for nanomedicine. We report here the …
with biosystems provides key foundational data for nanomedicine. We report here the …
A general mechanism for intracellular toxicity of metal-containing nanoparticles
The assessment of the risks exerted by nanoparticles is a key challenge for academic,
industrial, and regulatory communities worldwide. Experimental evidence points towards …
industrial, and regulatory communities worldwide. Experimental evidence points towards …
Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals
The structural and functional complexity of multicellular biological systems, such as the
brain, are beyond the reach of human design or assembly capabilities. Cells in living …
brain, are beyond the reach of human design or assembly capabilities. Cells in living …
Understanding nanoparticle cellular entry: a physicochemical perspective
CM Beddoes, CP Case, WH Briscoe - Advances in colloid and interface …, 2015 - Elsevier
Understanding interactions between nanoparticles (NPs) with biological matter, particularly
cells, is becoming increasingly important due to their growing application in medicine and …
cells, is becoming increasingly important due to their growing application in medicine and …