The cellular barriers are major bottlenecks for bioactive compounds entering into cells to
accomplish their biological functions, which limits their biomedical applications …

Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

Decades of nanotoxicology research have generated extensive and diverse data sets.
However, data is not equal to information. The question is how to extract critical information …

Nanoparticle size plays a central role in determining material properties and performance in
biomedical applications. A wide variety of functional nanomaterials and nano-bioconjugates …

We explore the potential of nanocrystals (a term used equivalently to nanoparticles) as
building blocks for nanomaterials, and the current advances and open challenges for …

The beneficial or deleterious effects of nanomedicines emerge from their complex
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …

Uptake, transport and toxicity of engineered nanomaterials (ENMs) into plant cells are
complex processes that are currently still not well understood. Parts of this problem are the …

The concept of DNA vaccination was introduced in the early 1990s. Since then,
advancements in the augmentation of the immunogenicity of DNA vaccines have brought …

Correlation of the surface physicochemical properties of nanoparticles with their interactions
with biosystems provides key foundational data for nanomedicine. We report here the …

The assessment of the risks exerted by nanoparticles is a key challenge for academic,
industrial, and regulatory communities worldwide. Experimental evidence points towards …