Steatotic liver disease (SLD) displays a dynamic and complex disease phenotype.
Consequently, the metabolic dysfunction-associated steatotic liver disease …

Bile acids (BAs) are a group of amphiphilic molecules consisting of a rigid steroid core
attached to a hydroxyl group with a varying number, position, and orientation, and a …

Nonalcoholic fatty liver disease (NAFLD) affects approximately 25% of the adult population
worldwide. This pathology can progress into end-stage liver disease with life-threatening …

Nonalcoholic fatty liver disease (NAFLD), a chronic condition associated with metabolic
dysfunction and obesity, has reached epidemic proportions worldwide. Although early …

Fibrotic remodelling is a highly conserved protective response to tissue injury and it is
essential for the maintenance of structural and functional tissue integrity. Also hepatic …

In humans, aging, triggers increased plasma concentrations of triglycerides, cholesterol, low-
density lipoproteins and lower capacity of high-density lipoproteins to remove cellular …

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease for which therapeutic
options are limited, with an unmet need to identify new therapeutic targets. IPF is thought to …

Our understanding of nonalcoholic steatohepatitis (NASH) pathophysiology continues to
advance rapidly. Given the complexity of the pathogenesis of NASH, the field has moved …

Nonalcoholic fatty liver disease (NAFLD) emerges as the most predominant cause of liver
disease, tightly linked to metabolic dysfunction. Bile acids (BAs), initially synthesized from …

Non-alcoholic fatty liver disease (NAFLD) presents a pervasive global pandemic, affecting
approximately 25% of the world's population. This grave health issue not only demands …