Stem cells have emerged as a key element of regenerative medicine therapies due to their
inherent ability to differentiate into a variety of cell phenotypes, thereby providing numerous …

Stem cells provide an alternative curative intervention for the infarcted heart by
compensating for the cardiomyocyte loss subsequent to myocardial injury. The presence of …

Stem cells hold great potential as cell-based therapies to promote vascularization and tissue
regeneration. However, the use of stem cells alone to promote angiogenesis remains limited …

Telocytes (TC s) are interstitial cells that are present in numerous organs, including the heart
interstitial space and cardiac stem cell niche. TCs are completely different from fibroblasts …

Tracking the fate and function of cells in vivo is paramount for the development of rational
therapies for cardiac injury. Bioluminescence imaging (BLI) provides a means for monitoring …

Currently, micro RNA (miRNA) is considered an attractive target for therapeutic intervention.
A significant obstacle to the miRNA-based treatments is the efficient delivery of miRNA to the …

Rationale: Previous studies have shown that human embryonic stem cell-derived
cardiomyocytes improved myocardial recovery when administered to infarcted pig and non …

The discovery of vascular endothelial growth factors (VEGFs) and their receptors has
considerably improved the understanding of the development and function of endothelial …

Current pharmacologic therapy for ischemic heart disease suffers multiple limitations such
as compliance issues and side effects of medications. Revascularization procedures often …

Objectives Shock waves have been shown to induce recruitment of intravenously injected
endothelial progenitor cells to ischemic hind limbs in rats. We hypothesized that shock wave …