OBJECTIVES: To consider methods and related evidence for evaluating bias in non-
randomised intervention studies. DATA SOURCES: Systematic reviews and methodological …

Delirium is characterized by a disturbance of consciousness with accompanying change in
cognition. Delirium typically manifests as a constellation of symptoms with an acute onset …

Alcohol-associated liver disease (ALD) is the most common cause of advanced hepatic
disease and frequent indication for liver transplantation worldwide. With harmful alcohol use …

Alcoholic liver disease (ALD) comprises a clinical-histologic spectrum including fatty liver,
alcoholic hepatitis (AH), and cirrhosis with its complications. Most patients are diagnosed at …

Alcoholic liver disease (ALD) is the most prevalent cause of advanced liver disease in
Europe. However, there has been limited research investment into ALD despite its …

Silymarin, a flavonolignan from′ milk thistle′(Silybum marianum) plant is used almost
exclusively for hepatoprotection and amounts to 180 million US dollars business in Germany …

Heavy drinking and alcohol use disorder are major public health problems. Practitioners not
specialising in alcohol treatment are often unaware of the guidelines for preventing …

Symptoms of alcohol withdrawal syndrome (AWS) may develop within 6–24 h after the
abrupt discontinuation or decrease of alcohol consumption. Symptoms can vary from …

Foreword This Journal feature begins with a case vignette highlighting a common clinical
problem. Evidence supporting various strategies is then presented, followed by a review of …

This review summarizes the current approaches to the management of withdrawal in
patients addicted to sedatives such as alcohol or benzodiazepines, opioids, or stimulants …