Therapeutically harnessing extracellular vesicles
The field of extracellular vesicle (EV) research has developed rapidly over the last decade
from the study of fundamental biology to a subject of significant clinical relevance. The …
from the study of fundamental biology to a subject of significant clinical relevance. The …
Exosomes: Large-scale production, isolation, drug loading efficiency, and biodistribution and uptake
I Kimiz-Gebologlu, SS Oncel - Journal of Controlled Release, 2022 - Elsevier
Exosomes are nanovesicles with different contents that play a role in various biological and
pathological processes. It offers significant advantages over other delivery systems such as …
pathological processes. It offers significant advantages over other delivery systems such as …
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …
origin and change the functions and phenotypes of other cells. These features indicate …
Extracellular vesicles as a next-generation drug delivery platform
Extracellular-vesicle-based cell-to-cell communication is conserved across all kingdoms of
life. There is compelling evidence that extracellular vesicles are involved in major (patho) …
life. There is compelling evidence that extracellular vesicles are involved in major (patho) …
A brief history of nearly EV‐erything–The rise and rise of extracellular vesicles
Extracellular vesicles (EVs) are small cargo‐bearing vesicles released by cells into the
extracellular space. The field of EVs has grown exponentially over the past two decades; this …
extracellular space. The field of EVs has grown exponentially over the past two decades; this …
Identification of storage conditions stabilizing extracellular vesicles preparations
Extracellular vesicles (EVs) play a key role in many physiological and pathophysiological
processes and hold great potential for therapeutic and diagnostic use. Despite significant …
processes and hold great potential for therapeutic and diagnostic use. Despite significant …
The power of imaging to understand extracellular vesicle biology in vivo
Extracellular vesicles (EVs) are nano-sized lipid bilayer vesicles released by virtually every
cell type. EVs have diverse biological activities, ranging from roles in development and …
cell type. EVs have diverse biological activities, ranging from roles in development and …
A paradigm shift in cell-free approach: the emerging role of MSCs-derived exosomes in regenerative medicine
S Moghadasi, M Elveny, HS Rahman… - Journal of translational …, 2021 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) due to their pro-angiogenic, anti-
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …
[HTML][HTML] Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications
Y Jia, L Yu, T Ma, W Xu, H Qian, Y Sun, H Shi - Theranostics, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles, especially small extracellular vesicles (sEVs) are now accepted as
important messengers in cell-to-cell communication and as a promising drug delivery …
important messengers in cell-to-cell communication and as a promising drug delivery …
[HTML][HTML] Extracellular vesicles as drug delivery systems: Why and how?
OM Elsharkasy, JZ Nordin, DW Hagey… - Advanced drug delivery …, 2020 - Elsevier
Over the past decades, a multitude of synthetic drug delivery systems has been developed
and introduced to the market. However, applications of such systems are limited due to …
and introduced to the market. However, applications of such systems are limited due to …