Ginsenoside Rg5: a review of anticancer and neuroprotection with network pharmacology approach

XF Gao, JJ Zhang, XJ Gong, KK Li… - The American Journal …, 2022 - World Scientific
Ginsenoside Rg5 (G-Rg5) is a rare ginsenoside isolated from ginseng (Panax ginseng CA
Meyer), and this compound is increasingly known for its potent pharmacological activities …

Network pharmacology based virtual screening of active constituents of Prunella vulgaris L. and the molecular mechanism against breast cancer

X Zhang, T Shen, X Zhou, X Tang, R Gao, L Xu… - Scientific reports, 2020 - nature.com
Prunella vulgaris L, a perennial herb widely used in Asia in the treatment of various
diseases including cancer. In vitro studies have demonstrated the therapeutic effect of …

Application of advanced technologies in natural product research: A review with special emphasis on ADMET profiling

P Borah, S Hazarika, S Deka… - Current Drug …, 2020 - ingentaconnect.com
The successful conversion of natural products (NPs) into lead compounds and novel
pharmacophores has emboldened the researchers to harness the drug discovery process …

Qing-Yi decoction in the treatment of acute pancreatitis: an integrated approach based on chemical profile, network pharmacology, molecular docking and …

TF Wei, L Zhao, P Huang, FL Hu, JY Jiao… - Frontiers in …, 2021 - frontiersin.org
Background: Qing-Yi Decoction (QYD) is a classic precompounded prescription with
satisfactory clinical efficacy on acute pancreatitis (AP). However, the chemical profile and …

Integrated computational strategies for Polypharmacological profiling and identification of anti‐inflammatory targets in Rungia pectinata L.

A Zaheen, S Rajkhowa, SA Al‐Hussain… - Journal of Cellular …, 2024 - Wiley Online Library
Rungia pectinata L. is an ethnomedicinal herb belonging to the Acanthaceae family and it
presents a promising avenue for medicinal exploration, deeply rooted in traditional …

Network pharmacology combined with molecular docking and experimental verification to elucidate functional mechanism of Fufang Zhenzhu Tiaozhi against type 2 …

B Li, X Li, Y Zeng, Z Zhou, D Zhao, F Qin… - Journal of …, 2024 - Taylor & Francis
Abstract Fufang Zhenzhu Tiaozhi (FTZ) capsules have been prescribed for treating glucose
and lipid metabolism disorders such as type 2 diabetes mellitus (T2DM). However, the …

A network pharmacological approach to reveal the pharmacological targets and its associated biological mechanisms of prunetin-5-o-glucoside against gastric cancer

P Vetrivel, R Murugesan, PB Bhosale, SE Ha, HH Kim… - Cancers, 2021 - mdpi.com
Simple Summary Identification of pharmacological targets in cancer provides a major
walkthrough toward treatment strategies. The present research adopted a network …

Implementation of system pharmacology and molecular docking approaches to explore active compounds and mechanism of ocimum sanctum against tuberculosis

S Tabassum, HR Khalid, W Haq, S Aslam… - Processes, 2022 - mdpi.com
Worldwide, Tuberculosis (TB) is caused by Mycobacterium tuberculosis bacteria. Ocimum
sanctum, commonly known as holy basil (Tulsi), is an herbaceous perennial that belongs to …

Feasibility of the inhibitor development for cancer: A systematic approach for drug design

Y Jiang, L Liu, Y Geng, Q Li, D Luo, L Liang, W Liu… - Plos one, 2024 - journals.plos.org
The traditional Chinese medicine (TCM) bupleurum-ginger-licorice formula presents
significant anti-cancer effects, but its active ingredients and inhibitory mechanism remain …

Network Pharmacology‐ and Molecular Docking‐Based Identification of Potential Phytocompounds from Argyreia capitiformis in the Treatment of Inflammation

AJ Obaidullah, MM Alanazi, NA Alsaif… - Evidence‐Based …, 2022 - Wiley Online Library
The methanolic extract of Argyreia capitiformis stem was examined for anti‐inflammatory
activities following network pharmacology analysis and molecular docking study. Based on …