Fluorescent analogs of biomolecular building blocks: design, properties, and applications
Fluorescence spectroscopy, one of the most informative and sensitive analytical techniques,
has played and continues to play key roles in modern research. Indeed, unraveling the inner …
has played and continues to play key roles in modern research. Indeed, unraveling the inner …
Environmentally sensitive fluorescent nucleoside analogues as probes for nucleic acid–protein interactions: molecular design and biosensing applications
D Dziuba - Methods and Applications in Fluorescence, 2022 - iopscience.iop.org
Fluorescent nucleoside analogues (FNAs) are indispensable in studying the interactions of
nucleic acids with nucleic acid-binding proteins. By replacing one of the poorly emissive …
nucleic acids with nucleic acid-binding proteins. By replacing one of the poorly emissive …
Ultrafast Dynamics in DNA:“Fraying” at the End of the Helix
D Andreatta, S Sen, JL Pérez Lustres… - Journal of the …, 2006 - ACS Publications
The dynamics of the electric fields in the interior of DNA are measured by using
oligonucleotides in which a native base pair is replaced by a dye molecule (coumarin 102) …
oligonucleotides in which a native base pair is replaced by a dye molecule (coumarin 102) …
Sequence-dependent fluorescence of Cy3-and Cy5-labeled double-stranded DNA
N Kretschy, M Sack, MM Somoza - Bioconjugate chemistry, 2016 - ACS Publications
The fluorescent intensity of Cy3 and Cy5 dyes is strongly dependent on the nucleobase
sequence of the labeled oligonucleotides. Sequence-dependent fluorescence may …
sequence of the labeled oligonucleotides. Sequence-dependent fluorescence may …
Power-law solvation dynamics in DNA over six decades in time
D Andreatta, JL Pérez Lustres… - Journal of the …, 2005 - ACS Publications
Time-resolved Stokes shifts in a dye-containing oligonucleotide have been observed over
the entire time range from 40 fs to 40 ns. The dynamics fit to a power law with a small …
the entire time range from 40 fs to 40 ns. The dynamics fit to a power law with a small …
Dynamics of water and ions near DNA: comparison of simulation to time-resolved stokes-shift experiments
S Sen, D Andreatta, SY Ponomarev… - Journal of the …, 2009 - ACS Publications
Time-resolved Stokes-shift experiments measure the dynamics of biomolecules and of the
perturbed solvent near them on subnanosecond time scales, but molecular dynamics …
perturbed solvent near them on subnanosecond time scales, but molecular dynamics …
8‐Vinyl‐2′‐deoxyguanosine as a fluorescent 2′‐deoxyguanosine mimic for investigating DNA hybridization and topology
A Nadler, J Strohmeier, U Diederichsen - … Chemie International Edition, 2011 - infona.pl
A one light strand: 2′‐Deoxyguanosine was made fluorescent by attaching a vinyl group at
the C8 position (see structure). The resulting fluorophore is highly sensitive towards DNA …
the C8 position (see structure). The resulting fluorophore is highly sensitive towards DNA …
Excited-state intramolecular proton transfer distinguishes microenvironments in single-and double-stranded DNA
AS Klymchenko, VV Shvadchak… - The Journal of …, 2008 - ACS Publications
Herein, the efficient interaction of an environment-sensitive fluorophore that undergoes
excited-state intramolecular proton transfer (ESIPT) with DNA has been realized by …
excited-state intramolecular proton transfer (ESIPT) with DNA has been realized by …
Thiazole orange and Cy3: Improvement of fluorescent DNA probes with use of short range electron transfer
F Menacher, M Rubner, S Berndl… - The Journal of organic …, 2008 - ACS Publications
Thiazole orange was synthetically incorporated into oligonucleotides by using the
corresponding phosphoramidite as the building block for automated DNA synthesis. Due to …
corresponding phosphoramidite as the building block for automated DNA synthesis. Due to …
Multiple time scales in solvation dynamics of DNA in aqueous solution: the role of water, counterions, and cross-correlations
Recent time domain experiments have explored solvation dynamics of a probe located
inside a DNA duplex, in an effort to gain information, eg, on the dynamics of water molecules …
inside a DNA duplex, in an effort to gain information, eg, on the dynamics of water molecules …