ELF topological analyses of bonding changes in non-polar, polar and ionic organic
reactions involving the participation of CC (X) double bonds make it possible to establish a …

Organic reactions that occur at the water interface for water-insoluble compounds, and
reactions in water solution for water soluble compounds, has added a powerful dimension to …

A good correlation between the activation energy and the polar character of Diels–Alder
reactions measured as the charge transfer at the transition state structure has been found …

Chemistry is the science of bond making and bond breaking. A thorough knowledge of these
processes in the course of the chemical reaction lies at the heart of any reaction mechanism …

The regioselective zw-type [3+ 2] cycloaddition (32CA) reactions of a series of aryl-
substituted nitrile N-oxides (NOs) with trichloronitropropene (TNP) have been both …

Abstract Chagas disease and Human African Trypanosomiasis (HAT) are caused by
Trypanosoma cruzi and T. brucei parasites, respectively. Cruzain (CRZ) and Rhodesain …

The tumor resistance to p53 activators posed a clinical challenge. Combination studies
disclosed that concomitant administration of Bcl2 inhibitors can sensitize the tumor cells and …

The carbenoid-type (cb-type) 32CA reaction of 1, 1-difluoroated azomethine ylide (DFAY)
with phenylpropynal has been studied using the molecular electron density theory (MEDT) …

Activation of inert sp3 β-C–H bonds has attracted widespread attention and been developed
with significant progress in recent years, but understanding the mechanism of this kind of …

The effects of metal-based Lewis acid (LA) catalysts on the reaction rate and regioselectivity
in polar Diels–Alder (P-DA) reactions has been analyzed within the molecular electron …